1: Mazurakova A, Koklesova L, Hurta Csizmár S, Samec M, Brockmüller A, Šudomová
M, Biringer K, Kudela E, Pec M, Mathews Samuel S, Kassayova M, Hassan STS,
Smejkal K, Shakibaei M, Büsselberg D, Saso L, Kubatka P, Golubnitschaja O.
Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in
therapy-resistant cancer cells - a potential contribution to the predictive,
preventive, and personalized medicine. J Adv Res. 2023 Mar
3:S2090-1232(23)00066-8. doi: 10.1016/j.jare.2023.02.015. Epub ahead of print.
PMID: 36871616.

2: Méndez-Valdés G, Gómez-Hevia F, Bragato MC, Lillo-Moya J, Rojas-Solé C, Saso
L, Rodrigo R. Antioxidant Protection against Trastuzumab Cardiotoxicity in
Breast Cancer Therapy. Antioxidants (Basel). 2023 Feb 10;12(2):457. doi:
10.3390/antiox12020457. PMID: 36830015; PMCID: PMC9952697.

3: Zhang J, Semlali A, Maycotte P, Saso L. Editorial: Targeting redox regulation
and autophagy systems for cancer therapy. Front Oncol. 2023 Jan 31;13:1146670.
doi: 10.3389/fonc.2023.1146670. PMID: 36798822; PMCID: PMC9927638.

4: Jacques MT, Saso L, Farina M. LPS-Activated Microglial Cell-Derived
Conditioned Medium Protects HT22 Neuronal Cells against Glutamate-Induced
Ferroptosis. Int J Mol Sci. 2023 Feb 2;24(3):2910. doi: 10.3390/ijms24032910.
PMID: 36769233; PMCID: PMC9917809.

5: Shahcheraghi SH, Salemi F, Small S, Syed S, Salari F, Alam W, Cheang WS, Saso
L, Khan H. Resveratrol regulates inflammation and improves oxidative stress via
Nrf2 signaling pathway: Therapeutic and biotechnological prospects. Phytother
Res. 2023 Feb 8. doi: 10.1002/ptr.7754. Epub ahead of print. PMID: 36752350.

6: Méndez-Valdés G, Pérez-Carreño V, Bragato MC, Hundahl M, Chichiarelli S, Saso
L, Rodrigo R. Cardioprotective Mechanisms against Reperfusion Injury in Acute
Myocardial Infarction: Targeting Angiotensin II Receptors. Biomedicines. 2022
Dec 22;11(1):17. doi: 10.3390/biomedicines11010017. PMID: 36672525; PMCID:
PMC9856001.

7: Hekmat A, Saso L, Lather V, Pandita D, Kostova I, Saboury AA. Recent Advances
in Nanomaterials of Group XIV Elements of Periodic Table in Breast Cancer
Treatment. Pharmaceutics. 2022 Nov 29;14(12):2640. doi:
10.3390/pharmaceutics14122640. PMID: 36559135; PMCID: PMC9781757.

8: Hussain Y, Abdullah, Khan F, Alsharif KF, Alzahrani KJ, Saso L, Khan H.
Regulatory Effects of Curcumin on Platelets: An Update and Future Directions.
Biomedicines. 2022 Dec 8;10(12):3180. doi: 10.3390/biomedicines10123180. PMID:
36551934; PMCID: PMC9775400.

9: Abelli J, Méndez-Valdés G, Gómez-Hevia F, Bragato MC, Chichiarelli S, Saso L,
Rodrigo R. Potential Antioxidant Multitherapy against Complications Occurring in
Sepsis. Biomedicines. 2022 Dec 1;10(12):3088. doi: 10.3390/biomedicines10123088.
PMID: 36551843; PMCID: PMC9775396.

10: Ávila C, Vinay JI, Arese M, Saso L, Rodrigo R. Antioxidant Intervention
against Male Infertility: Time to Design Novel Strategies. Biomedicines. 2022
Nov 28;10(12):3058. doi: 10.3390/biomedicines10123058. PMID: 36551814; PMCID:
PMC9775742.

11: Tucci P, Lattanzi R, Severini C, Saso L. Nrf2 Pathway in Huntington's
Disease (HD): What Is Its Role? Int J Mol Sci. 2022 Dec 3;23(23):15272. doi:
10.3390/ijms232315272. PMID: 36499596; PMCID: PMC9739588.

12: Mortazavi M, Divar M, Damghani T, Moosavi F, Saso L, Pirhadi S,
Khoshneviszadeh M, Edraki N, Firuzi O. Study of the anticancer effect of new
quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors.
Front Chem. 2022 Nov 17;10:969559. doi: 10.3389/fchem.2022.969559. PMID:
36465863; PMCID: PMC9713320.

13: Davinelli S, Medoro A, Intrieri M, Saso L, Scapagnini G, Kang JX. Targeting
NRF2-KEAP1 axis by Omega-3 fatty acids and their derivatives: Emerging
opportunities against aging and diseases. Free Radic Biol Med. 2022 Nov
20;193(Pt 2):736-750. doi: 10.1016/j.freeradbiomed.2022.11.017. Epub 2022 Nov
17. PMID: 36402440.

14: Gallorini M, Carradori S, Resende DISP, Saso L, Ricci A, Palmeira A, Cataldi
A, Pinto M, Sousa E. Natural and Synthetic Xanthone Derivatives Counteract
Oxidative Stress via Nrf2 Modulation in Inflamed Human Macrophages. Int J Mol
Sci. 2022 Nov 1;23(21):13319. doi: 10.3390/ijms232113319. PMID: 36362104; PMCID:
PMC9659273.

15: Profumo E, Maggi E, Arese M, Di Cristofano C, Salvati B, Saso L, Businaro R,
Buttari B. Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances
p62/SQSTM1-Dependent Autophagy and NRF2 Activation. Int J Mol Sci. 2022 Oct
27;23(21):13009. doi: 10.3390/ijms232113009. PMID: 36361795; PMCID: PMC9653849.

16: Sharifi S, Dalir Abdolahinia E, Ghavimi MA, Dizaj SM, Aschner M, Saso L,
Khan H. Effect of Curcumin-Loaded Mesoporous Silica Nanoparticles on the Head
and Neck Cancer Cell Line, HN5. Curr Issues Mol Biol. 2022 Oct
27;44(11):5247-5259. doi: 10.3390/cimb44110357. PMID: 36354669; PMCID:
PMC9688994.

17: Magnifico MC, Xhani M, Sprovera B, Buttari B, Abballe G, Desideri F, Panieri
E, Saso L, Arese M. Nitro-Oxidative Stress and Mitochondrial Dysfunction in
Human Cell Lines Exposed to the Environmental Contaminants PFOA and BPA. Front
Biosci (Landmark Ed). 2022 Oct 27;27(10):292. doi: 10.31083/j.fbl2710292. PMID:
36336871.

18: Panieri E, Telkoparan-Akillilar P, Saso L. NRF2, a crucial modulator of skin
cells protection against vitiligo, psoriasis, and cancer. Biofactors. 2022 Oct
30. doi: 10.1002/biof.1912. Epub ahead of print. PMID: 36310374.

19: Ghareghomi S, Habibi-Rezaei M, Arese M, Saso L, Moosavi-Movahedi AA. Nrf2
Modulation in Breast Cancer. Biomedicines. 2022 Oct 21;10(10):2668. doi:
10.3390/biomedicines10102668. PMID: 36289931; PMCID: PMC9599257.

20: Ahmed S, Alam W, Aschner M, Alsharif KF, Albrakati A, Saso L, Khan H.
Natural products targeting the ATR-CHK1 signaling pathway in cancer therapy.
Biomed Pharmacother. 2022 Nov;155:113797. doi: 10.1016/j.biopha.2022.113797.
Epub 2022 Oct 8. PMID: 36271573; PMCID: PMC9590097.

21: Buttari B, Arese M, Oberley-Deegan RE, Saso L, Chatterjee A. NRF2: A crucial
regulator for mitochondrial metabolic shift and prostate cancer progression.
Front Physiol. 2022 Sep 23;13:989793. doi: 10.3389/fphys.2022.989793. PMID:
36213236; PMCID: PMC9540504.

22: Roy A, Bera S, Saso L, Dwarakanath BS. Role of autophagy in tumor response
to radiation: Implications for improving radiotherapy. Front Oncol. 2022 Sep
12;12:957373. doi: 10.3389/fonc.2022.957373. PMID: 36172166; PMCID: PMC9510974.

23: Temaj G, Chichiarelli S, Eufemi M, Altieri F, Hadziselimovic R, Farooqi AA,
Yaylim I, Saso L. Ribosome-Directed Therapies in Cancer. Biomedicines. 2022 Aug
26;10(9):2088. doi: 10.3390/biomedicines10092088. PMID: 36140189; PMCID:
PMC9495564.

24: Ourhzif EM, Ricelli A, Stagni V, Cirigliano A, Rinaldi T, Bouissane L, Saso
L, Chalard P, Troin Y, Khouili M, Akssira M. Antifungal and Cytotoxic Activity
of Diterpenes and Bisnorsesquiterpenoides from the Latex of <i>Euphorbia
resinifera</i> Berg. Molecules. 2022 Aug 16;27(16):5234. doi:
10.3390/molecules27165234. PMID: 36014466; PMCID: PMC9413093.

25: Matlin SA, Smith AC, Merone J, LeVoy M, Shah J, Vanbiervliet F, Vandentorren
S, Vearey J, Saso L. The Challenge of Reaching Undocumented Migrants with
COVID-19 Vaccination. Int J Environ Res Public Health. 2022 Aug 12;19(16):9973.
doi: 10.3390/ijerph19169973. PMID: 36011606; PMCID: PMC9408401.

26: Gray NE, Farina M, Tucci P, Saso L. The Role of the NRF2 Pathway in
Maintaining and Improving Cognitive Function. Biomedicines. 2022 Aug
21;10(8):2043. doi: 10.3390/biomedicines10082043. PMID: 36009590; PMCID:
PMC9405981.

27: Egbujor MC, Buttari B, Profumo E, Telkoparan-Akillilar P, Saso L. An
Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their
Antioxidant Effects. Int J Mol Sci. 2022 Jul 30;23(15):8466. doi:
10.3390/ijms23158466. PMID: 35955599; PMCID: PMC9369284.

28: Panieri E, Pinho SA, Afonso GJM, Oliveira PJ, Cunha-Oliveira T, Saso L. NRF2
and Mitochondrial Function in Cancer and Cancer Stem Cells. Cells. 2022 Aug
4;11(15):2401. doi: 10.3390/cells11152401. PMID: 35954245; PMCID: PMC9367715.

29: Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, Saso L, Verbanac D. The
effect of multistrain probiotics on functional constipation in the elderly: a
randomized controlled trial. Eur J Clin Nutr. 2022 Dec;76(12):1675-1681. doi:
10.1038/s41430-022-01189-0. Epub 2022 Aug 4. PMID: 35927504; PMCID: PMC9708599.

30: Ahmed S, Alam W, Jeandet P, Aschner M, Alsharif KF, Saso L, Khan H.
Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic
Insights. Mar Drugs. 2022 Jul 22;20(8):466. doi: 10.3390/md20080466. PMID:
35892934; PMCID: PMC9330892.

31: Egbujor MC, Petrosino M, Zuhra K, Saso L. The Role of Organosulfur Compounds
as Nrf2 Activators and Their Antioxidant Effects. Antioxidants (Basel). 2022 Jun
26;11(7):1255. doi: 10.3390/antiox11071255. PMID: 35883746; PMCID: PMC9311638.

32: Hussain Y, Khan H, Alsharif KF, Hayat Khan A, Aschner M, Saso L. The
Therapeutic Potential of Kaemferol and Other Naturally Occurring Polyphenols
Might Be Modulated by Nrf2-ARE Signaling Pathway: Current Status and Future
Direction. Molecules. 2022 Jun 28;27(13):4145. doi: 10.3390/molecules27134145.
PMID: 35807387; PMCID: PMC9268049.

33: Hussain Y, Khan H, Alotaibi G, Khan F, Alam W, Aschner M, Jeandet P, Saso L.
How Curcumin Targets Inflammatory Mediators in Diabetes: Therapeutic Insights
and Possible Solutions. Molecules. 2022 Jun 24;27(13):4058. doi:
10.3390/molecules27134058. PMID: 35807304; PMCID: PMC9268477.

34: Hussain Y, Khan H, Alam W, Aschner M, Abdullah, Alsharif KF, Saso L.
Flavonoids Targeting the mTOR Signaling Cascades in Cancer: A Potential
Crosstalk in Anti-Breast Cancer Therapy. Oxid Med Cell Longev. 2022 Jun
27;2022:4831833. doi: 10.1155/2022/4831833. PMID: 35795855; PMCID: PMC9252758.

35: Temaj G, Saha S, Dragusha S, Ejupi V, Buttari B, Profumo E, Beqa L, Saso L.
Ribosomopathies and cancer: pharmacological implications. Expert Rev Clin
Pharmacol. 2022 Jun;15(6):729-746. doi: 10.1080/17512433.2022.2098110. Epub 2022
Jul 15. PMID: 35787725.

36: Suzen S, Tucci P, Profumo E, Buttari B, Saso L. A Pivotal Role of Nrf2 in
Neurodegenerative Disorders: A New Way for Therapeutic Strategies.
Pharmaceuticals (Basel). 2022 May 31;15(6):692. doi: 10.3390/ph15060692. PMID:
35745610; PMCID: PMC9227112.

37: González-Montero J, Chichiarelli S, Eufemi M, Altieri F, Saso L, Rodrigo R.
Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes
Back. Molecules. 2022 Jun 14;27(12):3818. doi: 10.3390/molecules27123818. PMID:
35744943; PMCID: PMC9229419.

38: Yaylım İ, Farooqi AA, Telkoparan-Akillilar P, Saso L. Interplay between Non-
Coding RNAs and NRF2 in Different Cancers: Spotlight on MicroRNAs and Long Non-
Coding RNAs. J Pharmacol Exp Ther. 2023 Jan;384(1):28-34. doi:
10.1124/jpet.121.000921. Epub 2022 Jun 6. PMID: 35667688.

39: Deus CM, Teixeira J, Raimundo N, Tucci P, Borges F, Saso L, Oliveira PJ.
Modulation of cellular redox environment as a novel therapeutic strategy for
Parkinson's disease. Eur J Clin Invest. 2022 Oct;52(10):e13820. doi:
10.1111/eci.13820. Epub 2022 Jun 13. PMID: 35638352.

40: Saso L, Reza A, Ng E, Nguyen K, Lin S, Zhang P, Fantozzi PJ, Armagan G,
Romeo U, Cirillo N. A Comprehensive Analysis of the Role of Oxidative Stress in
the Pathogenesis and Chemoprevention of Oral Submucous Fibrosis. Antioxidants
(Basel). 2022 Apr 28;11(5):868. doi: 10.3390/antiox11050868. PMID: 35624733;
PMCID: PMC9137539.

41: Janoušek J, Pilařová V, Macáková K, Nomura A, Veiga-Matos J, Silva DDD,
Remião F, Saso L, Malá-Ládová K, Malý J, Nováková L, Mladěnka P. Vitamin D:
sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity,
and overview of analytical methods for detection of vitamin D and its
metabolites. Crit Rev Clin Lab Sci. 2022 Dec;59(8):517-554. doi:
10.1080/10408363.2022.2070595. Epub 2022 May 16. PMID: 35575431.

42: Shahcheraghi SH, Salemi F, Alam W, Ashworth H, Saso L, Khan H, Lotfi M. The
Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications. Med
Oncol. 2022 May 15;39(5):91. doi: 10.1007/s12032-022-01693-0. PMID: 35568790.

43: Hussain Y, Abdullah, Alsharif KF, Aschner M, Theyab A, Khan F, Saso L, Khan
H. Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and
Therapeutic Potential. Nutrients. 2022 May 6;14(9):1949. doi:
10.3390/nu14091949. PMID: 35565917; PMCID: PMC9104383.

44: Guin D, Yadav S, Singh P, Singh P, Thakran S, Kukal S, Kanojia N, Paul PR,
Pattnaik B, Sardana V, Grover S, Hasija Y, Saso L, Agrawal A, Kukreti R. Human
genetic factors associated with pneumonia risk, a cue for COVID-19
susceptibility. Infect Genet Evol. 2022 Aug;102:105299. doi:
10.1016/j.meegid.2022.105299. Epub 2022 May 8. PMID: 35545162; PMCID:
PMC9080029.

45: Rodrigo R, Retamal C, Schupper D, Vergara-Hernández D, Saha S, Profumo E,
Buttari B, Saso L. Antioxidant Cardioprotection against Reperfusion Injury:
Potential Therapeutic Roles of Resveratrol and Quercetin. Molecules. 2022 Apr
15;27(8):2564. doi: 10.3390/molecules27082564. PMID: 35458766; PMCID:
PMC9027566.

46: Mohi-Ud-Din R, Mir RH, Wani TU, Alsharif KF, Alam W, Albrakati A, Saso L,
Khan H. The Regulation of Endoplasmic Reticulum Stress in Cancer: Special
Focuses on Luteolin Patents. Molecules. 2022 Apr 12;27(8):2471. doi:
10.3390/molecules27082471. PMID: 35458669; PMCID: PMC9031790.

47: Zaki M, Loubidi M, Bilgiç T, Birim D, Akssira M, Dagcı T, Berteina-Raboin S,
Saso L, Khouili M, Armagan G. Design, Synthesis, and Biological Evaluation of
Novel Tomentosin Derivatives in NMDA-Induced Excitotoxicity. Pharmaceuticals
(Basel). 2022 Mar 30;15(4):421. doi: 10.3390/ph15040421. PMID: 35455419; PMCID:
PMC9027110.

48: Gall Trošelj K, Tomljanović M, Jaganjac M, Matijević Glavan T, Čipak
Gašparović A, Milković L, Borović Šunjić S, Buttari B, Profumo E, Saha S, Saso
L, Žarković N. Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles
Relevant for Therapy Response. Molecules. 2022 Feb 22;27(5):1468. doi:
10.3390/molecules27051468. PMID: 35268568; PMCID: PMC8912061.

49: Panieri E, Baralic K, Djukic-Cosic D, Buha Djordjevic A, Saso L. PFAS
Molecules: A Major Concern for the Human Health and the Environment. Toxics.
2022 Jan 18;10(2):44. doi: 10.3390/toxics10020044. PMID: 35202231; PMCID:
PMC8878656.

50: Ahmed NS, Samec M, Liskova A, Kubatka P, Saso L. Tamoxifen and oxidative
stress: an overlooked connection. Discov Oncol. 2021 May 27;12(1):17. doi:
10.1007/s12672-021-00411-y. PMID: 35201439; PMCID: PMC8777555.

51: Singh A, Kukreti R, Saso L, Kukreti S. Mechanistic Insight into Oxidative
Stress-Triggered Signaling Pathways and Type 2 Diabetes. Molecules. 2022 Jan
30;27(3):950. doi: 10.3390/molecules27030950. PMID: 35164215; PMCID: PMC8840622.

52: Khan H, Alam W, Alsharif KF, Aschner M, Pervez S, Saso L. Alkaloids and
Colon Cancer: Molecular Mechanisms and Therapeutic Implications for Cell Cycle
Arrest. Molecules. 2022 Jan 28;27(3):920. doi: 10.3390/molecules27030920. PMID:
35164185; PMCID: PMC8838632.

53: Saso L, Chakrabarti S, Miller E. Pharmaceutical and Pharmacological Aspects
of Modulation of Oxidative Stress 2020. Oxid Med Cell Longev. 2022 Jan
27;2022:9842198. doi: 10.1155/2022/9842198. PMID: 35154577; PMCID: PMC8825295.

54: Brizzolari A, Foti MC, Saso L, Ciuffreda P, Lazarević J, Santaniello E.
Evaluation of the radical scavenging activity of some representative isoprenoid
and aromatic cytokinin ribosides (N<sup>6</sup>-substituted adenosines) by
<i>in vitro</i> chemical assays. Nat Prod Res. 2022 Dec;36(24):6443-6447. doi:
10.1080/14786419.2022.2037590. Epub 2022 Feb 7. PMID: 35130809.

55: Saha S, Buttari B, Profumo E, Tucci P, Saso L. A Perspective on Nrf2
Signaling Pathway for Neuroinflammation: A Potential Therapeutic Target in
Alzheimer's and Parkinson's Diseases. Front Cell Neurosci. 2022 Jan
21;15:787258. doi: 10.3389/fncel.2021.787258. PMID: 35126058; PMCID: PMC8813964.

56: Davinelli S, Saso L, D'Angeli F, Calabrese V, Intrieri M, Scapagnini G.
Astaxanthin as a Modulator of Nrf2, NF-κB, and Their Crosstalk: Molecular
Mechanisms and Possible Clinical Applications. Molecules. 2022 Jan 14;27(2):502.
doi: 10.3390/molecules27020502. PMID: 35056816; PMCID: PMC8779084.

57: Dimić DS, Kaluđerović GN, Avdović EH, Milenković DA, Živanović MN, Potočňák
I, Samoľová E, Dimitrijević MS, Saso L, Marković ZS, Dimitrić Marković JM.
Synthesis, Crystallographic, Quantum Chemical, Antitumor, and Molecular
Docking/Dynamic Studies of 4-Hydroxycoumarin-Neurotransmitter Derivatives. Int J
Mol Sci. 2022 Jan 17;23(2):1001. doi: 10.3390/ijms23021001. PMID: 35055194;
PMCID: PMC8780855.

58: Shahcheraghi SH, Salemi F, Peirovi N, Ayatollahi J, Alam W, Khan H, Saso L.
Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects.
Molecules. 2021 Dec 28;27(1):167. doi: 10.3390/molecules27010167. PMID:
35011412; PMCID: PMC8746993.

59: Mishra MK, Kukal S, Paul PR, Bora S, Singh A, Kukreti S, Saso L, Muthusamy
K, Hasija Y, Kukreti R. Insights into Structural Modifications of Valproic Acid
and Their Pharmacological Profile. Molecules. 2021 Dec 24;27(1):104. doi:
10.3390/molecules27010104. PMID: 35011339; PMCID: PMC8746633.

60: Talwar P, Kushwaha S, Rawat C, Kaur H, Srivastava A, Agarwal R, Chandna P,
Tucci P, Saso L, Kukreti R. Validating a Genomic Convergence and Network
Analysis Approach Using Association Analysis of Identified Candidate Genes in
Alzheimer's Disease. Front Genet. 2021 Dec 9;12:722221. doi:
10.3389/fgene.2021.722221. PMID: 34956307; PMCID: PMC8696000.

61: Seminotti B, Grings M, Tucci P, Leipnitz G, Saso L. Nuclear Factor
Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited
Metabolic Disorders. Front Cell Neurosci. 2021 Nov 26;15:785057. doi:
10.3389/fncel.2021.785057. PMID: 34955754; PMCID: PMC8693715.

62: Ghareghomi S, Rahban M, Moosavi-Movahedi Z, Habibi-Rezaei M, Saso L,
Moosavi-Movahedi AA. The Potential Role of Curcumin in Modulating the Master
Antioxidant Pathway in Diabetic Hypoxia-Induced Complications. Molecules. 2021
Dec 17;26(24):7658. doi: 10.3390/molecules26247658. PMID: 34946740; PMCID:
PMC8706440.

63: Costa M, Sezgin-Bayindir Z, Losada-Barreiro S, Paiva-Martins F, Saso L,
Bravo-Díaz C. Polyphenols as Antioxidants for Extending Food Shelf-Life and in
the Prevention of Health Diseases: Encapsulation and Interfacial Phenomena.
Biomedicines. 2021 Dec 14;9(12):1909. doi: 10.3390/biomedicines9121909. PMID:
34944722; PMCID: PMC8698762.

64: Banerjee A, Kanwar M, Das Mohapatra PK, Saso L, Nicoletti M, Maiti S.
Nigellidine (<i>Nigella sativa</i>, black-cumin seed) docking to SARS CoV-2 nsp3
and host inflammatory proteins may inhibit viral replication/transcription and
FAS-TNF death signal via TNFR 1/2 blocking. Nat Prod Res. 2022
Nov;36(22):5817-5822. doi: 10.1080/14786419.2021.2018430. Epub 2021 Dec 22.
PMID: 34937447.

65: Matlin SA, Karadag O, Brando CR, Góis P, Karabey S, Khan MMH, Saleh S,
Takian A, Saso L. COVID-19: Marking the Gaps in Migrant and Refugee Health in
Some Massive Migration Areas. Int J Environ Res Public Health. 2021 Nov
30;18(23):12639. doi: 10.3390/ijerph182312639. PMID: 34886367; PMCID:
PMC8657173.

66: Rahman N, Khan H, Zia A, Khan A, Fakhri S, Aschner M, Gul K, Saso L. Bcl-2
Modulation in p53 Signaling Pathway by Flavonoids: A Potential Strategy towards
the Treatment of Cancer. Int J Mol Sci. 2021 Oct 20;22(21):11315. doi:
10.3390/ijms222111315. PMID: 34768743; PMCID: PMC8582810.

67: Bisenieks E, Vigante B, Petrovska R, Turovska B, Muhamadejev R, Soloduns V,
Velena A, Pajuste K, Saso L, Klovins J, Duburs G, Mandrika I. The Specificity
and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors
FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor
HCA2/GPR109A. Pharmaceuticals (Basel). 2021 Sep 28;14(10):987. doi:
10.3390/ph14100987. PMID: 34681211; PMCID: PMC8537386.

68: Kukal S, Guin D, Rawat C, Bora S, Mishra MK, Sharma P, Paul PR, Kanojia N,
Grewal GK, Kukreti S, Saso L, Kukreti R. Multidrug efflux transporter ABCG2:
expression and regulation. Cell Mol Life Sci. 2021 Nov;78(21-22):6887-6939. doi:
10.1007/s00018-021-03901-y. Epub 2021 Sep 29. PMID: 34586444.

69: Marjanovic A, Djedjibegovic J, Lugusic A, Sober M, Saso L. Multivariate
analysis of polyphenolic content and in vitro antioxidant capacity of wild and
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70: Rodrigo R, Prieto JC, Aguayo R, Ramos C, Puentes Á, Gajardo A, Panieri E,
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2021 Sep 21;26(18):5702. doi: 10.3390/molecules26185702. PMID: 34577176; PMCID:
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71: Pierzynowska K, Gaffke L, Cyske Z, Węgrzyn G, Buttari B, Profumo E, Saso L.
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72: Tber Z, Loubidi M, Jouha J, Hdoufane I, Erdogan MA, Saso L, Armagan G,
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73: Koklesova L, Liskova A, Samec M, Zhai K, Al-Ishaq RK, Bugos O, Šudomová M,
Biringer K, Pec M, Adamkov M, Hassan STS, Saso L, Giordano FA, Büsselberg D,
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Mitochondriopathies and Associated Pathologies: Focus on the Predictive Approach
and Personalized Prevention. Int J Mol Sci. 2021 Aug 11;22(16):8649. doi:
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74: Farina M, Vieira LE, Buttari B, Profumo E, Saso L. The Nrf2 Pathway in
Ischemic Stroke: A Review. Molecules. 2021 Aug 18;26(16):5001. doi:
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75: Kumar A, Kaushik P, Incerpi S, Pedersen JZ, Goel S, Prasad AK, Rohil V,
Parmar VS, Saso L, Len C. Evaluation of the Free Radical Scavenging Activities
of Ellagic Acid and Ellagic Acid Peracetate by EPR Spectrometry. Molecules. 2021
Aug 8;26(16):4800. doi: 10.3390/molecules26164800. PMID: 34443388; PMCID:
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76: Szczuko M, Kikut J, Szczuko U, Szydłowska I, Nawrocka-Rutkowska J, Ziętek M,
Verbanac D, Saso L. Nutrition Strategy and Life Style in Polycystic Ovary
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77: Todorov L, Saso L, Benarous K, Traykova M, Linani A, Kostova I. Synthesis,
Structure and Impact of 5-Aminoorotic Acid and Its Complexes with Lanthanum(III)
and Gallium(III) on the Activity of Xanthine Oxidase. Molecules. 2021 Jul
26;26(15):4503. doi: 10.3390/molecules26154503. PMID: 34361656; PMCID:
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78: Matlin SA, Orcutt M, Bojorquez I, Caman OK, Severoni S, Spiegel P, Veizis A,
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in future pandemic preparedness. EClinicalMedicine. 2021 May 29;36:100904. doi:
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79: Verma S, Singh P, Khurana S, Ganguly NK, Kukreti R, Saso L, Rana DS, Taneja
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review on current concepts and therapies. Kidney Res Clin Pract. 2021
Jun;40(2):183-193. doi: 10.23876/j.krcp.20.163. Epub 2021 May 26. PMID:
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80: Ucar BI, Ucar G, Saha S, Buttari B, Profumo E, Saso L. Pharmacological
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81: Avdović EH, Petrović IP, Stevanović MJ, Saso L, Dimitrić Marković JM,
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82: Ganguly U, Kaur U, Chakrabarti SS, Sharma P, Agrawal BK, Saso L, Chakrabarti
S. Oxidative Stress, Neuroinflammation, and NADPH Oxidase: Implications in the
Pathogenesis and Treatment of Alzheimer's Disease. Oxid Med Cell Longev. 2021
Apr 16;2021:7086512. doi: 10.1155/2021/7086512. PMID: 33953837; PMCID:
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83: Sezgin-Bayindir Z, Losada-Barreiro S, Bravo-Díaz C, Sova M, Kristl J, Saso
L. Nanotechnology-Based Drug Delivery to Improve the Therapeutic Benefits of
NRF2 Modulators in Cancer Therapy. Antioxidants (Basel). 2021 Apr 27;10(5):685.
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84: Lillo-Moya J, Rojas-Solé C, Muñoz-Salamanca D, Panieri E, Saso L, Rodrigo R.
Targeting Ferroptosis against Ischemia/Reperfusion Cardiac Injury. Antioxidants
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85: Kancheva VD, Dettori MA, Fabbri D, Alov P, Angelova SE, Slavova-Kazakova AK,
Carta P, Menshov VA, Yablonskaya OI, Trofimov AV, Tsakovska I, Saso L. Natural
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86: Aleksic M, Kalezic A, Saso L, Jankovic A, Korac B, Korac A. The Unity of
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87: Süntar I, Çetinkaya S, Panieri E, Saha S, Buttari B, Profumo E, Saso L.
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2021 Apr 21;26(9):2424. doi: 10.3390/molecules26092424. PMID: 33919399; PMCID:
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88: Verbanac D, Čeri A, Hlapčić I, Shakibaei M, Brockmueller A, Krušlin B,
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Štefanović M, Ćelap I, Demirović A, Petlevski R, Petrik J, Grdić Rajković M,
Hulina-Tomašković A, Rako I, Saso L, Barišić K. Profiling Colorectal Cancer in
the Landscape Personalized Testing-Advantages of Liquid Biopsy. Int J Mol Sci.
2021 Apr 21;22(9):4327. doi: 10.3390/ijms22094327. PMID: 33919272; PMCID:
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89: Buha A, Baralić K, Djukic-Cosic D, Bulat Z, Tinkov A, Panieri E, Saso L. The
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90: Telkoparan-Akillilar P, Panieri E, Cevik D, Suzen S, Saso L. Therapeutic
Targeting of the NRF2 Signaling Pathway in Cancer. Molecules. 2021 Mar
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91: Tascioglu Aliyev A, Panieri E, Stepanić V, Gurer-Orhan H, Saso L.
Involvement of NRF2 in Breast Cancer and Possible Therapeutical Role of
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92: Ulker OC, Panieri E, Suzen S, Jaganjac M, Zarkovic N, Saso L. Short overview
on the relevance of microRNA-reactive oxygen species (ROS) interactions and
lipid peroxidation for modulation of oxidative stress-mediated signalling
pathways in cancer treatment. J Pharm Pharmacol. 2022 Apr 20;74(4):503-515. doi:
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93: Banerjee A, Ganguly U, Saha S, Chakrabarti S, Saini RV, Rawal RK, Saso L,
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94: Lattanzi R, Severini C, Maftei D, Saso L, Badiani A. The Role of
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95: Egbujor MC, Saha S, Buttari B, Profumo E, Saso L. Activation of Nrf2
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96: Damghani T, Moosavi F, Khoshneviszadeh M, Mortazavi M, Pirhadi S, Kayani Z,
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antiproliferative effect on lung and pancreatic cancer cells and potentially
inhibit receptor tyrosine kinases including c-Met. Sci Rep. 2021 Feb
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97: Urrutia I, Martín-Nieto A, Martínez R, Casanovas-Marsal JO, Aguayo A, Del
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98: García-Castaño A, Madariaga L, Gómez-Conde S, Cordo CLR, López-Iglesias M,
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99: Maslovarić I, Ilić V, Drvenica I, Stančić A, Mojsilović S, Kukolj T,
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100: Zaiter J, Hibot A, Hafid A, Khouili M, Neves CMB, Simões MMQ, Neves MGPMS,
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101: Panieri E, Saso L. Inhibition of the NRF2/KEAP1 Axis: A Promising
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102: Tancheva L, Lazarova M, Saso L, Kalfin R, Stefanova M, Uzunova D, Atanasov
AG. Beneficial Effect of Melatonin on Motor and Memory Disturbances in 6-OHDA-
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103: Samec M, Liskova A, Koklesova L, Mersakova S, Strnadel J, Kajo K, Pec M,
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A, Shakibaei M, Büsselberg D, Kubatka P. Flavonoids Targeting HIF-1:
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104: Viayna E, Coquelle N, Cieslikiewicz-Bouet M, Cisternas P, Oliva CA,
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Pons M, Firuzi O, Pérez B, Saso L, Andrisano V, Nachon F, Brazzolotto X, García
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105: Guin D, Rani J, Singh P, Grover S, Bora S, Talwar P, Karthikeyan M,
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106: Ricelli A, Gionfra F, Percario Z, De Angelis M, Primitivo L, Bonfantini V,
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107: Rahban M, Habibi-Rezaei M, Mazaheri M, Saso L, Moosavi-Movahedi AA. Anti-
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108: Cunha-Oliveira T, Montezinho L, Mendes C, Firuzi O, Saso L, Oliveira PJ,
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109: Todorov L, Traykova M, Saso L, Kostova I. In Vitro Interaction of
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110: Saha S, Buttari B, Panieri E, Profumo E, Saso L. An Overview of Nrf2
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111: Nabavi SM, Devi KP, Sathya S, Sanches-Silva A, Joanna L, Talarek S, Xu S,
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L. New Trends in the Pharmacological Intervention of PPARs in Obesity: Role of
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112: Benarous K, Bou-Salah L, Linani A, Yousfi M, Kostova I, Saso L. Lanthanide
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113: Thakran S, Guin D, Singh P, Singh P, Kukal S, Rawat C, Yadav S, Kushwaha
SS, Srivastava AK, Hasija Y, Saso L, Ramachandran S, Kukreti R. Genetic
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114: Saha S, Profumo E, Togna AR, Riganò R, Saso L, Buttari B. Lupeol
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Cholesterol: New Perspectives in the Therapy of Atherosclerosis. Oxid Med Cell
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115: García-Castaño A, Madariaga L, Antón-Gamero M, Mejia N, Ponce J, Gómez-
Conde S, Pérez de Nanclares G, De la Hoz AB, Martínez R, Saso L, Martínez de
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116: Kaur U, Chakrabarti SS, Ojha B, Pathak BK, Singh A, Saso L, Chakrabarti S.
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117: Kaur U, Acharya K, Mondal R, Singh A, Saso L, Chakrabarti S, Chakrabarti
SS. Should ACE2 be given a chance in COVID-19 therapeutics: A semi-systematic
review of strategies enhancing ACE2. Eur J Pharmacol. 2020 Nov 15;887:173545.
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118: Alam W, Khan H, Shah MA, Cauli O, Saso L. Kaempferol as a Dietary Anti-
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119: Zarneshan SN, Fakhri S, Farzaei MH, Khan H, Saso L. Astaxanthin targets
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120: Djedjibegovic J, Marjanovic A, Panieri E, Saso L. Ellagic Acid-Derived
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121: Nagarajan S, Nagarajan R, Kumar J, Salemme A, Togna AR, Saso L, Bruno F.
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122: Saso L, Gürer-Orhan H, Stepanić V. Modulators of Oxidative Stress: Chemical
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123: Sova M, Saso L. Natural Sources, Pharmacokinetics, Biological Activities
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124: Losada-Barreiro S, Sova M, Mravljak J, Saso L, Bravo-Díaz C. Synthesis, In
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Phenolic Compound in Olive Oil-In-Water Emulsions. Antioxidants (Basel). 2020
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125: Panieri E, Telkoparan-Akillilar P, Suzen S, Saso L. The NRF2/KEAP1 Axis in
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126: Sheath D, Flahault A, Seybold J, Saso L. Diverse and Complex Challenges to
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127: Saso L, Suzen S, Borges F, Csont T. Chemistry and Pharmacology of
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128: Shahraki O, Khoshneviszadeh M, Dehghani M, Mohabbati M, Tavakkoli M, Saso
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129: Albert A, Paul E, Rajakumar S, Saso L. Oxidative stress and endoplasmic
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130: Panieri E, Buha A, Telkoparan-Akillilar P, Cevik D, Kouretas D, Veskoukis
A, Skaperda Z, Tsatsakis A, Wallace D, Suzen S, Saso L. Potential Applications
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131: Rawat C, Kutum R, Kukal S, Srivastava A, Dahiya UR, Kushwaha S, Sharma S,
Dash D, Saso L, Srivastava AK, Kukreti R. Downregulation of peripheral
PTGS2/COX-2 in response to valproate treatment in patients with epilepsy. Sci
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132: Saha S, Panieri E, Suzen S, Saso L. The Interaction of Flavonols with
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133: Nallathamby N, Phan CW, Sova M, Saso L, Sabaratnam V. Synthesized
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134: Najmanová I, Vopršalová M, Saso L, Mladěnka P. The pharmacokinetics of
flavanones. Crit Rev Food Sci Nutr. 2020;60(18):3155-3171. doi:
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135: Carbone C, Lo Russo SLM, Lacivita E, Frank A, Alleva E, Stark H, Saso L,
Leopoldo M, Adriani W. Prior Activation of 5-HT7 Receptors Modulates the
Conditioned Place Preference With Methylphenidate. Front Behav Neurosci. 2019
Sep 18;13:208. doi: 10.3389/fnbeh.2019.00208. PMID: 31619973; PMCID: PMC6759476.

136: Moosavi F, Giovannetti E, Saso L, Firuzi O. HGF/MET pathway aberrations as
diagnostic, prognostic, and predictive biomarkers in human cancers. Crit Rev
Clin Lab Sci. 2019 Dec;56(8):533-566. doi: 10.1080/10408363.2019.1653821. Epub
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137: Singh A, Kukreti R, Saso L, Kukreti S. Oxidative Stress: Role and Response
of Short Guanine Tracts at Genomic Locations. Int J Mol Sci. 2019 Aug
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138: Buttari B, Profumo E, Capozzi A, Saso L, Sorice M, Riganò R. Post-
translational modifications of proteins in antiphospholipid antibody syndrome.
Crit Rev Clin Lab Sci. 2019 Dec;56(8):511-525. doi:
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139: Guin D, Rani J, Singh P, Grover S, Bora S, Talwar P, Karthikeyan M,
Satyamoorthy K, Adithan C, Ramachandran S, Saso L, Hasija Y, Kukreti R. Global
Text Mining and Development of Pharmacogenomic Knowledge Resource for Precision
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140: Smith RE, Ozben T, Saso L. Modulation of Oxidative Stress: Pharmaceutical
and Pharmacological Aspects 2018. Oxid Med Cell Longev. 2019 Jul 3;2019:6380473.
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141: Faure A, Zoratto F, Chirico D, Romano E, Mancinelli R, Saso L, Callebert J,
Laviola G, Granon S, Adriani W. Reduced adolescent risk-assessment and lower
nicotinic beta-2 expression in rats exposed to nicotine through lactation by
forcedly drinking dams. Neuroscience. 2019 Aug 10;413:64-76. doi:
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142: Divya G, Albert A, Singab ANB, Ayoub IM, Al-Sayed E, Paul E, Manoharan K,
Saso L, Selvam GS. Renoprotective effect of tectorigenin glycosides isolated
from <i>Iris spuria</i> L. (Zeal) against hyperoxaluria and hyperglycemia in
NRK-49Fcells. Nat Prod Res. 2021 Mar;35(6):1029-1034. doi:
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143: Velkov Z, Traykov M, Trenchev I, Saso L, Tadjer A. Topology-Dependent
Dissociation Mode of the O-H Bond in Monohydroxycoumarins. J Phys Chem A. 2019
Jun 20;123(24):5106-5113. doi: 10.1021/acs.jpca.9b00535. Epub 2019 Jun 7. PMID:
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144: Panieri E, Saso L. Potential Applications of NRF2 Inhibitors in Cancer
Therapy. Oxid Med Cell Longev. 2019 Apr 11;2019:8592348. doi:
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145: Firuzi O, Che PP, El Hassouni B, Buijs M, Coppola S, Löhr M, Funel N,
Heuchel R, Carnevale I, Schmidt T, Mantini G, Avan A, Saso L, Peters GJ,
Giovannetti E. Role of c-MET Inhibitors in Overcoming Drug Resistance in
Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells. Cancers
(Basel). 2019 May 8;11(5):638. doi: 10.3390/cancers11050638. PMID: 31072019;
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146: Telkoparan-Akillilar P, Suzen S, Saso L. Pharmacological Applications of
Nrf2 Inhibitors as Potential Antineoplastic Drugs. Int J Mol Sci. 2019 Apr
24;20(8):2025. doi: 10.3390/ijms20082025. PMID: 31022969; PMCID: PMC6514836.

147: Srivastava A, Singh P, Gupta H, Kaur H, Kanojia N, Guin D, Sood M, Chadda
RK, Yadav J, Vohora D, Saso L, Kukreti R. Systems Approach to Identify Common
Genes and Pathways Associated with Response to Selective Serotonin Reuptake
Inhibitors and Major Depression Risk. Int J Mol Sci. 2019 Apr 23;20(8):1993.
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148: Singh A, Kukreti R, Saso L, Kukreti S. Oxidative Stress: A Key Modulator in
Neurodegenerative Diseases. Molecules. 2019 Apr 22;24(8):1583. doi:
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149: Armagan G, Sevgili E, Gürkan FT, Köse FA, Bilgiç T, Dagcı T, Saso L.
Regulation of the Nrf2 Pathway by Glycogen Synthase Kinase-3β in MPP⁺-Induced
Cell Damage. Molecules. 2019 Apr 8;24(7):1377. doi: 10.3390/molecules24071377.
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150: Stepanić V, Matijašić M, Horvat T, Verbanac D, Kučerová-Chlupáčová M, Saso
L, Žarković N. Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives
of Chalcones-In Vitro and In Silico Study. Antioxidants (Basel). 2019 Apr
5;8(4):90. doi: 10.3390/antiox8040090. PMID: 30959820; PMCID: PMC6523444.

151: Bempong NE, Sheath D, Seybold J, Flahault A, Depoux A, Saso L. Critical
reflections, challenges and solutions for migrant and refugee health: 2nd M8
Alliance Expert Meeting. Public Health Rev. 2019 Mar 19;40:3. doi:
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152: Jankovic A, Saso L, Korac A, Korac B. Relation of Redox and Structural
Alterations of Rat Skin in the Function of Chronological Aging. Oxid Med Cell
Longev. 2019 Feb 14;2019:2471312. doi: 10.1155/2019/2471312. PMID: 30906501;
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153: Dimić DS, Marković ZS, Saso L, Avdović EH, Đorović JR, Petrović IP,
Stanisavljević DD, Stevanović MJ, Potočňák I, Samoľová E, Trifunović SR,
Dimitrić Marković JM. Synthesis and Characterization of
3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential
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154: Beara I, Majkić T, Fioravanti S, Trulli L, Mimica-Dukić N, Pellacani L,
Saso L. The Effects of Trifluoromethylated Derivatives on Prostaglandin E2 and
Thromboxane A2 Production in Human Leukemic U937 Macrophages. Med Chem.
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155: Macáková K, Afonso R, Saso L, Mladěnka P. The influence of alkaloids on
oxidative stress and related signaling pathways. Free Radic Biol Med. 2019
Apr;134:429-444. doi: 10.1016/j.freeradbiomed.2019.01.026. Epub 2019 Jan 29.
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156: Zuhra K, Sousa PMF, Paulini G, Lemos AR, Kalme Z, Bisenieks I, Bisenieks E,
Vigante B, Duburs G, Bandeiras TM, Saso L, Giuffrè A, Vicente JB. Screening
Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by
Orthogonal Methods. Sci Rep. 2019 Jan 24;9(1):684. doi:
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157: Hosseini R, Moosavi F, Silva T, Rajaian H, Hosseini SY, Bina S, Saso L,
Miri R, Borges F, Firuzi O. Modulation of ERK1/2 and Akt Pathways Involved in
the Neurotrophic Action of Caffeic Acid Alkyl Esters. Molecules. 2018 Dec
17;23(12):3340. doi: 10.3390/molecules23123340. PMID: 30562988; PMCID:
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158: Ranjbar S, Khonkarn R, Moreno A, Baubichon-Cortay H, Miri R,
Khoshneviszadeh M, Saso L, Edraki N, Falson P, Firuzi O. 5-Oxo-
hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters
to overcome multidrug resistance in cancer cells. Toxicol Appl Pharmacol. 2019
Jan 1;362:136-149. doi: 10.1016/j.taap.2018.10.025. Epub 2018 Nov 2. PMID:
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159: Sova M, Saso L. Design and development of Nrf2 modulators for cancer
chemoprevention and therapy: a review. Drug Des Devel Ther. 2018 Sep
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160: Ranjbar S, Firuzi O, Edraki N, Shahraki O, Saso L, Khoshneviszadeh M, Miri
R. Tetrahydroquinolinone derivatives as potent P-glycoprotein inhibitors:
design, synthesis, biological evaluation and molecular docking analysis.
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161: Profumo E, Buttari B, Tinaburri L, D'Arcangelo D, Sorice M, Capozzi A,
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Riganò R. Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary
Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin
in Preventing HSP90 Exposure to the Immune System. Oxid Med Cell Longev. 2018
Apr 10;2018:2373167. doi: 10.1155/2018/2373167. PMID: 29849874; PMCID:
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162: Muronetz VI, Melnikova AK, Saso L, Schmalhausen EV. Influence of Oxidative
Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate
Dehydrogenase. Curr Med Chem. 2020;27(13):2040-2058. doi:
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163: Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M. Nonylphenol and
Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide
Signaling. Oxid Med Cell Longev. 2018 Apr 2;2018:1684827. doi:
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164: Talwar P, Gupta R, Kushwaha S, Agarwal R, Saso L, Kukreti S, Kukreti R.
Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease
Pathogenesis with Identification of Potential Drug Candidates: A Systematic
Review using Systems Biology Approach. Curr Neuropharmacol. 2019;17(4):352-365.
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165: Djukic M, Fesatidou M, Xenikakis I, Geronikaki A, Angelova VT, Savic V,
Pasic M, Krilovic B, Djukic D, Gobeljic B, Pavlica M, Djuric A, Stanojevic I,
Vojvodic D, Saso L. In vitro antioxidant activity of thiazolidinone derivatives
of 1,3-thiazole and 1,3,4-thiadiazole. Chem Biol Interact. 2018 Apr
25;286:119-131. doi: 10.1016/j.cbi.2018.03.013. Epub 2018 Mar 21. PMID:
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166: Bloch S, Nejman-Faleńczyk B, Pierzynowska K, Piotrowska E, Węgrzyn A,
Marminon C, Bouaziz Z, Nebois P, Jose J, Le Borgne M, Saso L, Węgrzyn G.
Inhibition of Shiga toxin-converting bacteriophage development by novel
antioxidant compounds. J Enzyme Inhib Med Chem. 2018 Dec;33(1):639-650. doi:
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167: Catapano MC, Karlíčková J, Tvrdý V, Sharma S, Prasad AK, Saso L, Chhillar
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derivatives: Copper chelation and reduction ability. J Trace Elem Med Biol. 2018
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168: Saso L, Korkina L, Zarkovic N. Modulation of Oxidative Stress:
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169: Kancheva VD, Slavova-Kazakova AK, Angelova SE, Kumar P, Malhotra S, Singh
BK, Saso L, Prasad AK, Parmar VS. Protective effects of new antioxidant
compositions of 4-methylcoumarins and related compounds with dl-α-tocopherol and
l-ascorbic acid. J Sci Food Agric. 2018 Aug;98(10):3784-3794. doi:
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170: Loubidi M, Jouha J, Tber Z, Khouili M, Suzenet F, Akssira M, Erdogan MA,
Köse FA, Dagcı T, Armagan G, Saso L, Guillaumet G. Efficient synthesis and first
regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold
and their evaluation in H<sub>2</sub>O<sub>2</sub>-induced oxidative stress. Eur
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171: Applova L, Veljovic E, Muratovic S, Karlickova J, Macakova K, Zavrsnik D,
Saso L, Duric K, Mladenka P. 9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-
xanthene-3-one is a Potentially Novel Antiplatelet Drug which Antagonizes the
Effect of Thromboxane A2. Med Chem. 2018 Feb 6;14(2):200-209. doi:
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172: Grewal GK, Kukal S, Kanojia N, Madan K, Saso L, Kukreti R. In Vitro
Assessment of the Effect of Antiepileptic Drugs on Expression and Function of
ABC Transporters and Their Interactions with ABCC2. Molecules. 2017 Sep
29;22(10):1484. doi: 10.3390/molecules22101484. PMID: 28961159; PMCID:
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173: Kancheva VD, Slavova-Kazakova AK, Angelova SE, Singh SK, Malhotra S, Singh
BK, Saso L, Prasad AK, Parmar VS. Protective effects of 4-methylcoumarins and
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174: Menezes JCJMDS, Edraki N, Kamat SP, Khoshneviszadeh M, Kayani Z, Mirzaei
HH, Miri R, Erfani N, Nejati M, Cavaleiro JAS, Silva T, Saso L, Borges F, Firuzi
O. Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer
Agents: Selective Induction of Apoptosis in Cancer Cells. J Agric Food Chem.
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175: Gurer-Orhan H, Ince E, Konyar D, Saso L, Suzen S. The Role of Oxidative
Stress Modulators in Breast Cancer. Curr Med Chem. 2018;25(33):4084-4101. doi:
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176: Ganesan D, Al-Sayed E, Albert A, Paul E, Singab ANB, Govindan Sadasivam S,
Saso L. Antioxidant activity of phenolic compounds from extracts of Eucalyptus
globulus and Melaleuca styphelioides and their protective role on D-glucose-
induced hyperglycemic stress and oxalate stress in NRK-49Fcells. Nat Prod Res.
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177: Graziani M, Sarti P, Arese M, Magnifico MC, Badiani A, Saso L.
Cardiovascular Mitochondrial Dysfunction Induced by Cocaine: Biomarkers and
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178: Moosavi F, Hosseini R, Rajaian H, Silva T, Magalhães E Silva D, Saso L,
Edraki N, Miri R, Borges F, Firuzi O. Derivatives of caffeic acid, a natural
antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic
agents. Bioorg Med Chem. 2017 Jun 15;25(12):3235-3246. doi:
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179: Boldrini P, Fusco A, Nicoletti F, Badiani A, Saso L. Potential Use of
Modulators of Oxidative Stress as Add-on Therapy in Patients with Anxiety
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180: Milkovic L, Zarkovic N, Saso L. Controversy about pharmacological
modulation of Nrf2 for cancer therapy. Redox Biol. 2017 Aug;12:727-732. doi:
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181: Joshi R, Rohil V, Arora S, Manral S, Kumar A, Goel S, Priya N, Singh P,
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Kohli E, DePass AL, Bracke ME, Parmar VS, Raj HG. Corrigendum to The Competence
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182: Ganguly G, Chakrabarti S, Chatterjee U, Saso L. Proteinopathy, oxidative
stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and
Parkinson's disease. Drug Des Devel Ther. 2017 Mar 16;11:797-810. doi:
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183: Grewal GK, Kukal S, Kanojia N, Saso L, Kukreti S, Kukreti R. Effect of
Oxidative Stress on ABC Transporters: Contribution to Epilepsy
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184: Shahraki O, Edraki N, Khoshneviszadeh M, Zargari F, Ranjbar S, Saso L,
Firuzi O, Miri R. Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis,
in vitro P-glycoprotein-mediated multidrug resistance reversal profile and
molecular dynamics simulation study. Drug Des Devel Ther. 2017 Feb
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185: Jouha J, Loubidi M, Bouali J, Hamri S, Hafid A, Suzenet F, Guillaumet G,
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compounds based on pyrazolopyridine scaffold and evaluation of their
neuroprotective potential in MPP<sup>+</sup>-induced neurodegeneration. Eur J
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186: Albert A, Tiwari V, Paul E, Ganesan D, Ayyavu M, Kujur R, Ponnusamy S,
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decarboxylase in HEK293 cells confers protection against oxalate induced
oxidative stress as a therapeutic approach for calcium oxalate stone disease. J
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187: Suzen S, Gurer-Orhan H, Saso L. Detection of Reactive Oxygen and Nitrogen
Species by Electron Paramagnetic Resonance (EPR) Technique. Molecules. 2017 Jan
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188: Begic A, Djuric A, Ninkovic M, Stevanovic I, Djurdjevic D, Pavlovic M,
Jelic K, Pantelic A, Zebic G, Dejanovic B, Stanojevic I, Vojvodic D,
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hepatic redox status of rats subchronically exposed to cadmium. J Enzyme Inhib
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189: Angelova VT, Valcheva V, Vassilev NG, Buyukliev R, Momekov G, Dimitrov I,
Saso L, Djukic M, Shivachev B. Antimycobacterial activity of novel hydrazide-
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190: Brizzolari A, Campisi GM, Santaniello E, Razzaghi-Asl N, Saso L, Foti MC.
Effect of organic co-solvents in the evaluation of the hydroxyl radical
scavenging activity by the 2-deoxyribose degradation assay: The paradigmatic
case of α-lipoic acid. Biophys Chem. 2017 Jan;220:1-6. doi:
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191: Hosseini R, Moosavi F, Rajaian H, Silva T, Magalhães E Silva D, Soares P,
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192: Jović M, Cerović S, Zolotarevska L, Gačević M, Stanojević I, Miller K,
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expression of survivin with histopathological parameters of cutaneous melanoma.
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193: Malhotra S, Tavakkoli M, Edraki N, Miri R, Sharma SK, Prasad AK, Saso L,
Len C, Parmar VS, Firuzi O. Neuroprotective and Antioxidant Activities of
4-Methylcoumarins: Development of Structure-Activity Relationships. Biol Pharm
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194: Verbanac D, Malik R, Chand M, Kushwaha K, Vashist M, Matijašić M, Stepanić
V, Perić M, Paljetak HČ, Saso L, Jain SC. Synthesis and evaluation of
antibacterial and antioxidant activity of novel 2-phenyl-quinoline analogs
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195: Phan CW, Sabaratnam V, Bovicelli P, Righi G, Saso L. Negletein as a
neuroprotectant enhances the action of nerve growth factor and induces neurite
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196: Carvalho AN, Firuzi O, Gama MJ, Horssen JV, Saso L. Oxidative Stress and
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197: Korkina L, Ozben T, Saso L. Modulation of Oxidative Stress: Pharmaceutical
and Pharmacological Aspects. Oxid Med Cell Longev. 2016;2016:6023417. doi:
10.1155/2016/6023417. Epub 2016 Feb 24. PMID: 27006747; PMCID: PMC4783544.

198: Gurer-Orhan H, Karaaslan C, Ozcan S, Firuzi O, Tavakkoli M, Saso L, Suzen
S. Novel indole-based melatonin analogues: Evaluation of antioxidant activity
and protective effect against amyloid β-induced damage. Bioorg Med Chem. 2016
Apr 15;24(8):1658-64. doi: 10.1016/j.bmc.2016.02.039. Epub 2016 Mar 2. PMID:
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199: Cort A, Ozben T, Saso L, De Luca C, Korkina L. Redox Control of Multidrug
Resistance and Its Possible Modulation by Antioxidants. Oxid Med Cell Longev.
2016;2016:4251912. doi: 10.1155/2016/4251912. Epub 2016 Jan 5. PMID: 26881027;
PMCID: PMC4736404.

200: Graziani M, Antonilli L, Togna AR, Grassi MC, Badiani A, Saso L.
Cardiovascular and Hepatic Toxicity of Cocaine: Potential Beneficial Effects of
Modulators of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:8408479. doi:
10.1155/2016/8408479. Epub 2015 Dec 28. PMID: 26823954; PMCID: PMC4707355.

201: Moosavi F, Hosseini R, Saso L, Firuzi O. Modulation of neurotrophic
signaling pathways by polyphenols. Drug Des Devel Ther. 2015 Dec 21;10:23-42.
doi: 10.2147/DDDT.S96936. PMID: 26730179; PMCID: PMC4694682.

202: Filipský T, Mladenka P, Macáková K, Hrdina R, Saso L, Marchetti F,
Pettinari C. Effect of novel 1-phenyl-3-methyl-4-acylpyrazolones on iron
chelation and Fenton reaction. Free Radic Biol Med. 2014 Oct;75 Suppl 1:S29-30.
doi: 10.1016/j.freeradbiomed.2014.10.758. Epub 2014 Dec 10. PMID: 26461329.

203: Khoshaman K, Yousefi R, Tamaddon AM, Saso L, Moosavi-Movahedi AA. The
impact of Hydrogen peroxide on structure, stability and functional properties of
Human R12C mutant αA-crystallin: The imperative insights into pathomechanism of
the associated congenital cataract incidence. Free Radic Biol Med. 2015
Dec;89:819-30. doi: 10.1016/j.freeradbiomed.2015.09.013. Epub 2015 Oct 12. PMID:
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204: Djuric A, Begic A, Gobeljic B, Stanojevic I, Ninkovic M, Vojvodic D,
Pantelic A, Zebic G, Prokic V, Dejanovic B, Stojanovic I, Pavlica M, Djukic D,
Saso L, Djurdjevic D, Pavlovic M, Topic A, Vujanovic D, Stevnovic I, Djukic M.
Oxidative stress, bioelements and androgen status in testes of rats subacutely
exposed to cadmium. Food Chem Toxicol. 2015 Dec;86:25-33. doi:
10.1016/j.fct.2015.09.004. Epub 2015 Sep 16. PMID: 26385724.

205: Martin J, Mladěnka P, Saso L, Kostova I. Lanthanide(III) complexes are more
active inhibitors of the Fenton reaction than pure ligands. Redox Rep. 2016
Mar;21(2):84-9. doi: 10.1179/1351000215Y.0000000031. Epub 2016 Feb 18. PMID:
26193444; PMCID: PMC6837644.

206: Miri R, Nejati M, Saso L, Khakdan F, Parshad B, Mathur D, Parmar VS, Bracke
ME, Prasad AK, Sharma SK, Firuzi O. Structure-activity relationship studies of
4-methylcoumarin derivatives as anticancer agents. Pharm Biol.
2016;54(1):105-10. doi: 10.3109/13880209.2015.1016183. Epub 2015 May 27. PMID:
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207: Miller E, Morel A, Saso L, Saluk J. Melatonin redox activity. Its potential
clinical applications in neurodegenerative disorders. Curr Top Med Chem.
2015;15(2):163-9. PMID: 25985818.

208: Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological
target for medicinal chemistry: synthesis and evaluation of compounds with redox
activity - part 4. Curr Top Med Chem. 2015;15(9):821. doi:
10.2174/156802661509150320111829. PMID: 25821976.

209: Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological
target for medicinal chemistry: synthesis and evaluation of compounds with redox
activity--part 3. Curr Top Med Chem. 2015;15(5):414. doi:
10.2174/156802661505150223095720. PMID: 25714430.

210: Ramprasath T, Vasudevan V, Sasikumar S, Puhari SS, Saso L, Selvam GS.
Regression of oxidative stress by targeting eNOS and Nrf2/ARE signaling: a
guided drug target for cardiovascular diseases. Curr Top Med Chem.
2015;15(9):857-71. doi: 10.2174/1568026615666150220114417. PMID: 25697563.

211: Ivanovska N, Saso L, Dimitrov P. Kinase inhibitors with redox and anti-
inflammatory activities. Curr Top Med Chem. 2015;15(9):872-85. doi:
10.2174/1568026615666150220115838. PMID: 25697562.

212: Das KK, Razzaghi-Asl N, Tikare SN, Di Santo R, Costi R, Messore A,
Pescatori L, Crucitti GC, Jargar JG, Dhundasi SA, Saso L. Hypoglycemic activity
of curcumin synthetic analogues in alloxan-induced diabetic rats. J Enzyme Inhib
Med Chem. 2016;31(1):99-105. doi: 10.3109/14756366.2015.1004061. Epub 2015 Feb
16. PMID: 25683079.

213: Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological
target for medicinal chemistry: synthesis and evaluation of compounds with redox
activity - part 2. Curr Top Med Chem. 2015;15(2):84. doi:
10.2174/1568026615666150120151459. PMID: 25599751.

214: Joshi R, Rohil V, Arora S, Kumar A, Manral S, Goel S, Priya N, Singh P,
Ponnan P, Chatterji S, Dwarakanath BS, Saluja D, Rawat DS, Prasad AK, Saso L,
Kohli E, DePass AL, Bracke ME, Parmar VS, Raj HG. The Competence of
7,8-Diacetoxy-4-Methylcoumarin and Other Polyphenolic Acetates in Mitigating the
Oxidative Stress and their Role in Angiogenesis. Curr Top Med Chem.
2015;15(2):179-86. Erratum in: Curr Top Med Chem. 2017;17 (9):1115. PMID:
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215: Miller E, Morel A, Saso L, Saluk J. Melatonin Redox Activity. Its Potential
Clinical Application in Neurodegenerative Disorders. Curr Top Med Chem. 2014 Dec
29. Epub ahead of print. PMID: 25547102.

216: Borges F, Saso L, Garrido J, Suzen S. Oxidative stress as a pharmacological
target for medicinal chemistry: synthesis and evaluation of compounds with redox
activity - part 1. Curr Top Med Chem. 2014;14(22):2461. doi:
10.2174/1568026615666141216121823. PMID: 25515767.

217: Joshi R, Arora S, Kumar A, Manral S, Rohil V, Goel S, Priya N, Singh P,
Ponnan P, Chatterji S, Dwarakanath BS, Saluja D, Rawat DS, Prasad AK, Saso L,
Kohli E, DePass AL, Bracke ME, Parmar VS, Raj HG. The Competence Of
7,8-Diacetoxy-4-Methylcoumarinand Other Polyphenolic Acetates In Mitigating The
Oxidative Stress And Their Role In Angiogenesis. Curr Top Med Chem. 2014 Dec 9.
Epub ahead of print. PMID: 25496273.

218: Venkateswaran K, Verma A, Bhatt AN, Agrawala PK, Raj HG, Malhotra S, Prasad
AK, Wever OD, Bracke ME, Saso L, Parmar VS, Shrivastava A, Dwarakanath BS.
Modifications of cell signalling and redox balance by targeting protein
acetylation using natural and engineered molecules: implications in cancer
therapy. Curr Top Med Chem. 2014;14(22):2495-507. doi:
10.2174/1568026614666141203122005. PMID: 25478886.

219: Valcheva-Traykova M, Saso L, Kostova I. Involvement of lanthanides in the
free radicals homeostasis. Curr Top Med Chem. 2014;14(22):2508-19. doi:
10.2174/1568026614666141203123620. PMID: 25478885.

220: Muronetz V, Asryants R, Semenyuk P, Schmalhausen E, Saso L. Hydrophobic
plant antioxidants. Preparation of nanoparticles and their application for
prevention of neurodegenerative diseases. Review and experimental data. Curr Top
Med Chem. 2014;14(22):2520-8. doi: 10.2174/1568026614666141203124057. PMID:
25478884.

221: Profumo E, Buttari B, Saso L, Rigano R. Pleiotropic effects of statins in
atherosclerotic disease: focus on the antioxidant activity of atorvastatin. Curr
Top Med Chem. 2014;14(22):2542-51. doi: 10.2174/1568026614666141203130324. PMID:
25478882.

222: Shekari F, Sadeghpour H, Javidnia K, Saso L, Nazari F, Firuzi O, Miri R.
Cytotoxic and multidrug resistance reversal activities of novel
1,4-dihydropyridines against human cancer cells. Eur J Pharmacol. 2015 Jan
5;746:233-44. doi: 10.1016/j.ejphar.2014.10.058. Epub 2014 Nov 14. PMID:
25445037.

223: Saso L, Firuzi O. Pharmacological applications of antioxidants: lights and
shadows. Curr Drug Targets. 2014;15(13):1177-99. doi:
10.2174/1389450115666141024113925. PMID: 25341421.

224: Chandak N, Bhardwaj JK, Zheleva-Dimitrova D, Kitanov G, Sharma RK, Sharma
PK, Saso L. Effective attenuation of atrazine-induced histopathological changes
in testicular tissue by antioxidant N-phenyl-4-aryl-polyhydroquinolines. J
Enzyme Inhib Med Chem. 2015;30(5):722-9. doi: 10.3109/14756366.2014.960864.
PMID: 25265324.

225: Banerjee P, Sahoo A, Anand S, Ganguly A, Righi G, Bovicelli P, Saso L,
Chakrabarti S. Multiple mechanisms of iron-induced amyloid beta-peptide
accumulation in SHSY5Y cells: protective action of negletein. Neuromolecular
Med. 2014 Dec;16(4):787-98. doi: 10.1007/s12017-014-8328-4. Epub 2014 Sep 24.
PMID: 25249289.

226: Tavakkoli M, Miri R, Jassbi AR, Erfani N, Asadollahi M, Ghasemi M, Saso L,
Firuzi O. Carthamus, Salvia and Stachys species protect neuronal cells against
oxidative stress-induced apoptosis. Pharm Biol. 2014 Dec;52(12):1550-7. doi:
10.3109/13880209.2014.908394. Epub 2014 Sep 22. PMID: 25243877.

227: Buttari B, Profumo E, Segoni L, D'Arcangelo D, Rossi S, Facchiano F, Saso
L, Businaro R, Iuliano L, Riganò R. Resveratrol counteracts inflammation in
human M1 and M2 macrophages upon challenge with 7-oxo-cholesterol: potential
therapeutic implications in atherosclerosis. Oxid Med Cell Longev.
2014;2014:257543. doi: 10.1155/2014/257543. Epub 2014 May 8. PMID: 24895526;
PMCID: PMC4034709.

228: Miller E, Morel A, Saso L, Saluk J. Isoprostanes and neuroprostanes as
biomarkers of oxidative stress in neurodegenerative diseases. Oxid Med Cell
Longev. 2014;2014:572491. doi: 10.1155/2014/572491. Epub 2014 Apr 29. PMID:
24868314; PMCID: PMC4020162.

229: Ponnan P, Kumar A, Singh P, Gupta P, Joshi R, Gaspari M, Saso L, Prasad AK,
Rastogi RC, Parmar VS, Raj HG. Comparison of protein acetyltransferase action of
CRTAase with the prototypes of HAT. ScientificWorldJournal. 2014 Feb
4;2014:578956. doi: 10.1155/2014/578956. PMID: 24688408; PMCID: PMC3932232.

230: Togna AR, Firuzi O, Latina V, Parmar VS, Prasad AK, Salemme A, Togna GI,
Saso L. 4-Methylcoumarin derivatives with anti-inflammatory effects in activated
microglial cells. Biol Pharm Bull. 2014;37(1):60-6. doi: 10.1248/bpb.b13-00568.
PMID: 24389482.

231: Borges F, Saso L, Garrido J, Suzen S. Synthesis, evaluation and
pharmacological applications of antioxidants- part 2. Curr Med Chem.
2013;20(37):4647. doi: 10.2174/092986732037131118112721. PMID: 24274815.

232: Borges F, Saso L, Garrido J, Suzen S. Synthesis, evaluation and
pharmacological applications of antioxidants- part 1. Curr Med Chem.
2013;20(36):4435. doi: 10.2174/0929867311320360001. PMID: 24206123.

233: Buttari B, Profumo E, Facchiano F, Ozturk EI, Segoni L, Saso L, Riganò R.
Resveratrol prevents dendritic cell maturation in response to advanced glycation
end products. Oxid Med Cell Longev. 2013;2013:574029. doi: 10.1155/2013/574029.
Epub 2013 Jul 9. PMID: 23936610; PMCID: PMC3725714.

234: Kostova I, Saso L. Advances in research of Schiff-base metal complexes as
potent antioxidants. Curr Med Chem. 2013;20(36):4609-32. doi:
10.2174/09298673113209990149. PMID: 23834186.

235: Buttari B, Profumo E, Businaro R, Saso L, Capoano R, Salvati B, Riganò R.
Oxidized haemoglobin-driven endothelial dysfunction and immune cell activation:
novel therapeutic targets for atherosclerosis. Curr Med Chem.
2013;20(37):4806-14. doi: 10.2174/09298673113209990162. PMID: 23834168.

236: Tsvetkova D, Obreshkova D, Zheleva-Dimitrova D, Saso L. Antioxidant
activity of galantamine and some of its derivatives. Curr Med Chem.
2013;20(36):4595-608. doi: 10.2174/09298673113209990148. PMID: 23834167.

237: Firuzi O, Javidnia K, Mansourabadi E, Saso L, Mehdipour AR, Miri R.
Reversal of multidrug resistance in cancer cells by novel asymmetrical
1,4-dihydropyridines. Arch Pharm Res. 2013 Nov;36(11):1392-402. doi:
10.1007/s12272-013-0149-8. Epub 2013 May 15. PMID: 23674129.

238: Lombardo E, Sabellico C, Hájek J, Staňková V, Filipský T, Balducci V, De
Vito P, Leone S, Bavavea EI, Silvestri IP, Righi G, Luly P, Saso L, Bovicelli P,
Pedersen JZ, Incerpi S. Protection of cells against oxidative stress by
nanomolar levels of hydroxyflavones indicates a new type of intracellular
antioxidant mechanism. PLoS One. 2013 Apr 18;8(4):e60796. doi:
10.1371/journal.pone.0060796. PMID: 23637768; PMCID: PMC3630532.

239: Suzen S, Saso L. Editorial: antioxidant heterocyclic compounds in drug
discovery and medicinal chemistry. Mini Rev Med Chem. 2013 Mar;13(3):317. PMID:
23441620.

240: Profumo E, Buttari B, Saso L, Capoano R, Salvati B, Riganò R. T lymphocyte
autoreactivity in inflammatory mechanisms regulating atherosclerosis.
ScientificWorldJournal. 2012;2012:157534. doi: 10.1100/2012/157534. Epub 2012
Dec 10. PMID: 23304078; PMCID: PMC3529860.

241: Kumar A, Ponnan P, Raj HG, Parmar VS, Saso L. Comparative specificities of
Calreticulin Transacetylase to O-acetyl, N-acetyl and S-acetyl derivative of
4-methylcoumarins and their inhibitory effect on AFB1-induced genotoxicity in
vitro and in vivo. Food Chem Toxicol. 2013 Feb;52:216-24. doi:
10.1016/j.fct.2012.11.018. Epub 2012 Nov 23. PMID: 23182742.

242: Macáková K, Řeháková Z, Mladěnka P, Karlíčková J, Filipský T, Říha M,
Prasad AK, Parmar VS, Jahodář L, Pávek P, Hrdina R, Saso L. In vitro platelet
antiaggregatory properties of 4-methylcoumarins. Biochimie. 2012
Dec;94(12):2681-6. doi: 10.1016/j.biochi.2012.09.006. Epub 2012 Sep 17. PMID:
22996069.

243: Macáková K, Mladěnka P, Filipský T, Říha M, Jahodář L, Trejtnar F,
Bovicelli P, Proietti Silvestri I, Hrdina R, Saso L. Iron reduction potentiates
hydroxyl radical formation only in flavonols. Food Chem. 2012 Dec
15;135(4):2584-92. doi: 10.1016/j.foodchem.2012.06.107. Epub 2012 Jul 14. PMID:
22980846.

244: Verbanac D, Jain SC, Jain N, Chand M, Cipčić Paljetak H, Matijašić M, Perić
M, Stepanić V, Saso L. An efficient and convenient microwave-assisted chemical
synthesis of (thio)xanthones with additional in vitro and in silico
characterization. Bioorg Med Chem. 2012 May 15;20(10):3180-5. doi:
10.1016/j.bmc.2012.03.074. Epub 2012 Apr 6. PMID: 22537683.

245: Profumo E, Di Franco M, Buttari B, Masella R, Filesi C, Tosti ME, Scrivo R,
Scarno A, Spadaro A, Saso L, Riganò R. Biomarkers of subclinical atherosclerosis
in patients with autoimmune disorders. Mediators Inflamm. 2012;2012:503942. doi:
10.1155/2012/503942. Epub 2012 Feb 22. PMID: 22529523; PMCID: PMC3317012.

246: Garrido J, Gaspar A, Garrido EM, Miri R, Tavakkoli M, Pourali S, Saso L,
Borges F, Firuzi O. Alkyl esters of hydroxycinnamic acids with improved
antioxidant activity and lipophilicity protect PC12 cells against oxidative
stress. Biochimie. 2012 Apr;94(4):961-7. doi: 10.1016/j.biochi.2011.12.015. Epub
2011 Dec 23. PMID: 22210493.

247: Filipský T, Mladěnka P, Macáková K, Hrdina R, Saso L, Marchetti F,
Pettinari C. In vitro characteristics of 1-phenyl-3-methyl-4-acylpyrazol-5-ones
iron chelators. Biochimie. 2012 Jan;94(1):125-31. doi:
10.1016/j.biochi.2011.09.024. Epub 2011 Oct 4. PMID: 21986369.

248: Adriani W, Travaglini D, Lacivita E, Saso L, Leopoldo M, Laviola G.
Modulatory effects of two novel agonists for serotonin receptor 7 on emotion,
motivation and circadian rhythm profiles in mice. Neuropharmacology. 2012
Feb;62(2):833-42. doi: 10.1016/j.neuropharm.2011.09.012. Epub 2011 Sep 19. PMID:
21945717.

249: Kancheva VD, Saso L, Angelova SE, Foti MC, Slavova-Kasakova A, Daquino C,
Enchev V, Firuzi O, Nechev J. Antiradical and antioxidant activities of new bio-
antioxidants. Biochimie. 2012 Feb;94(2):403-15. doi:
10.1016/j.biochi.2011.08.008. Epub 2011 Aug 25. PMID: 21884748.

250: Firuzi O, Miri R, Tavakkoli M, Saso L. Antioxidant therapy: current status
and future prospects. Curr Med Chem. 2011;18(25):3871-88. doi:
10.2174/092986711803414368. PMID: 21824100.

251: Kostova I, Bhatia S, Grigorov P, Balkansky S, Parmar VS, Prasad AK, Saso L.
Coumarins as antioxidants. Curr Med Chem. 2011;18(25):3929-51. doi:
10.2174/092986711803414395. PMID: 21824098.

252: Barzegar A, Pedersen JZ, Incerpi S, Moosavi-Movahedi AA, Saso L. The
mechanism of antioxidant activity of IRFI005 as a synthetic hydrophilic analogue
of vitamin E. Biochimie. 2011 Oct;93(10):1880-8. doi:
10.1016/j.biochi.2011.07.019. Epub 2011 Jul 23. PMID: 21802483.

253: Trapani L, Segatto M, Simeoni V, Balducci V, Dhawan A, Parmar VS, Prasad
AK, Saso L, Incerpi S, Pallottini V. Short- and long-term regulation of
3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin.
Biochimie. 2011 Jul;93(7):1165-71. doi: 10.1016/j.biochi.2011.04.009. Epub 2011
Apr 23. PMID: 21530605.

254: Manral S, Bhatia S, Sinha R, Kumar A, Rohil V, Arya A, Dhawan A, Arya P,
Joshi R, Sreedhara SC, Gangopadhyay S, Bansal SK, Chatterjee S, Chaudhury NK,
Vijayan VK, Saso L, Parmar VS, DePass AL, Prasad AK, Raj HG. Normalization of
deranged signal transduction in lymphocytes of COPD patients by the novel
calcium channel blocker H-DHPM. Biochimie. 2011 Jul;93(7):1146-56. doi:
10.1016/j.biochi.2011.04.004. Epub 2011 Apr 20. PMID: 21527308.

255: Buttari B, Profumo E, Capozzi A, Facchiano F, Saso L, Sorice M, Riganò R.
Advanced glycation end products of human β₂ glycoprotein I modulate the
maturation and function of DCs. Blood. 2011 Jun 9;117(23):6152-61. doi:
10.1182/blood-2010-12-325514. Epub 2011 Apr 15. PMID: 21498672.

256: Mladěnka P, Macáková K, Filipský T, Zatloukalová L, Jahodář L, Bovicelli P,
Silvestri IP, Hrdina R, Saso L. In vitro analysis of iron chelating activity of
flavonoids. J Inorg Biochem. 2011 May;105(5):693-701. doi:
10.1016/j.jinorgbio.2011.02.003. Epub 2011 Feb 16. PMID: 21450273.

257: Singh P, Ponnan P, Priya N, Tyagi TK, Gaspari M, Krishnan S, Cuda G, Joshi
P, Gambhir JK, Sharma SK, Prasad AK, Saso L, Rastogi RC, Parmar VS, Raj HG.
Protein acyltransferase function of purified calreticulin: the exclusive role of
P-domain in mediating protein acylation utilizing acyloxycoumarins and acetyl
CoA as the acyl group donors. Protein Pept Lett. 2011 May;18(5):507-17. doi:
10.2174/092986611794927938. PMID: 21235489.

258: Gaspar A, Martins M, Silva P, Garrido EM, Garrido J, Firuzi O, Miri R, Saso
L, Borges F. Dietary phenolic acids and derivatives. Evaluation of the
antioxidant activity of sinapic acid and its alkyl esters. J Agric Food Chem.
2010 Nov 10;58(21):11273-80. doi: 10.1021/jf103075r. Epub 2010 Oct 15. PMID:
20949946.

259: Kaushik R, Marwah RG, Gupta P, Saran S, Saso L, Parmar VS, Saxena RK.
Optimization of Lipase Production from Aspergillus terreus by Response Surface
Methodology and Its Potential for Synthesis of Partial Glycerides Under Solvent
Free Conditions. Indian J Microbiol. 2010 Oct;50(4):456-62. doi:
10.1007/s12088-011-0100-y. Epub 2011 Jan 25. PMID: 22282615; PMCID: PMC3209838.

260: Le-Thi-Thu H, Casañola-Martín GM, Marrero-Ponce Y, Rescigno A, Saso L,
Parmar VS, Torrens F, Abad C. Novel coumarin-based tyrosinase inhibitors
discovered by OECD principles-validated QSAR approach from an enlarged, balanced
database. Mol Divers. 2011 May;15(2):507-20. doi: 10.1007/s11030-010-9274-1.
Epub 2010 Sep 3. PMID: 20814821.

261: Petrucci R, Saso L, Kumar V, Prasad AK, Malhotra SV, Parmar VS, Marrosu G.
A spectroelectrochemical and chemical study on oxidation of
7,8-dihydroxy-4-methylcoumarin (DHMC) and some related compounds in aprotic
medium. Biochimie. 2010 Sep;92(9):1123-9. doi: 10.1016/j.biochi.2010.06.008.
Epub 2010 Jun 17. PMID: 20600572.

262: Kancheva VD, Saso L, Boranova PV, Khan A, Saroj MK, Pandey MK, Malhotra S,
Nechev JZ, Sharma SK, Prasad AK, Georgieva MB, Joseph C, DePass AL, Rastogi RC,
Parmar VS. Structure-activity relationship of dihydroxy-4-methylcoumarins as
powerful antioxidants: correlation between experimental & theoretical data and
synergistic effect. Biochimie. 2010 Sep;92(9):1089-100. doi:
10.1016/j.biochi.2010.06.012. Epub 2010 Jun 19. PMID: 20600568.

263: Gupta P, Balwani S, Kumar S, Aggarwal N, Rossi M, Paumier S, Caruso F,
Bovicelli P, Saso L, DePass AL, Prasad AK, Parmar VS, Ghosh B. beta-sitosterol
among other secondary metabolites of Piper galeatum shows inhibition of
TNFalpha-induced cell adhesion molecule expression on human endothelial cells.
Biochimie. 2010 Sep;92(9):1213-21. doi: 10.1016/j.biochi.2010.06.005. Epub 2010
Jun 15. PMID: 20558233.

264: Natella F, Lorrain B, Prasad AK, Parmar VS, Saso L, Scaccini C.
4-methylcoumarins as antioxidants: scavenging of peroxyl radicals and inhibition
of human low-density lipoprotein oxidation. Biochimie. 2010 Sep;92(9):1147-52.
doi: 10.1016/j.biochi.2010.04.019. Epub 2010 Apr 29. PMID: 20434515.

265: Morabito G, Trombetta D, Singh Brajendra K, Prasad Ashok K, Parmar Virinder
S, Naccari C, Mancari F, Saija A, Cristani M, Firuzi O, Saso L. Antioxidant
properties of 4-methylcoumarins in in vitro cell-free systems. Biochimie. 2010
Sep;92(9):1101-7. doi: 10.1016/j.biochi.2010.04.017. Epub 2010 Apr 28. PMID:
20433892.

266: Mladenka P, Macáková K, Zatloukalová L, Reháková Z, Singh BK, Prasad AK,
Parmar VS, Jahodár L, Hrdina R, Saso L. In vitro interactions of coumarins with
iron. Biochimie. 2010 Sep;92(9):1108-14. doi: 10.1016/j.biochi.2010.03.025. Epub
2010 Apr 8. PMID: 20381579.

267: Singh P, Ponnan P, Krishnan S, Tyagi TK, Priya N, Bansal S, Scumaci D,
Gaspari M, Cuda G, Joshi P, Gambhir JK, Saluja D, Prasad AK, Saso L, Rastogi RC,
Parmar VS, Raj HG. Protein acyltransferase function of purified calreticulin.
Part 1: characterization of propionylation of protein utilizing propoxycoumarin
as the propionyl group donor. J Biochem. 2010 May;147(5):625-32. doi:
10.1093/jb/mvq002. Epub 2010 Jan 12. PMID: 20071373.

268: Koot S, Adriani W, Saso L, van den Bos R, Laviola G. Home cage testing of
delay discounting in rats. Behav Res Methods. 2009 Nov;41(4):1169-76. doi:
10.3758/BRM.41.4.1169. PMID: 19897825.

269: Macrì S, Granstrem O, Shumilina M, Antunes Gomes dos Santos FJ, Berry A,
Saso L, Laviola G. Resilience and vulnerability are dose-dependently related to
neonatal stressors in mice. Horm Behav. 2009 Oct;56(4):391-8. doi:
10.1016/j.yhbeh.2009.07.006. Epub 2009 Jul 24. PMID: 19632235.

270: Dimitrova P, Gyurkovska V, Shalova I, Saso L, Ivanovska N. Inhibition of
zymosan-induced kidney dysfunction by tyrphostin AG-490. J Inflamm (Lond). 2009
May 5;6:13. doi: 10.1186/1476-9255-6-13. PMID: 19416544; PMCID: PMC2687438.

271: Manconia M, Pendás J, Ledón N, Moreira T, Sinico C, Saso L, Fadda AM.
Phycocyanin liposomes for topical anti-inflammatory activity: in-vitro in-vivo
studies. J Pharm Pharmacol. 2009 Apr;61(4):423-30. doi: 10.1211/jpp/61.04.0002.
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272: Arora S, Tyagi YK, Kumar A, Majumder S, Saluja D, Raj HG, Chatterjee S,
Saso L, Prasad AK, Parmar VS. The role of calreticulin transacetylase in the
activation of human platelet nitrite reductase by polyphenolic acetates. Biol
Pharm Bull. 2009 Feb;32(2):161-5. doi: 10.1248/bpb.32.161. PMID: 19182369.

273: Bansal S, Ponnan P, Raj HG, Weintraub ST, Chopra M, Kumari R, Saluja D,
Kumar A, Tyagi TK, Singh P, Prasad AK, Saso L, Rastogi RC, Parmar VS.
Autoacetylation of purified calreticulin transacetylase utilizing
acetoxycoumarin as the acetyl group donor. Appl Biochem Biotechnol. 2009
May;157(2):285-98. doi: 10.1007/s12010-008-8357-2. Epub 2008 Sep 16. Erratum in:
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274: Naletova I, Schmalhausen E, Kharitonov A, Katrukha A, Saso L, Caprioli A,
Muronetz V. Non-native glyceraldehyde-3-phosphate dehydrogenase can be an
intrinsic component of amyloid structures. Biochim Biophys Acta. 2008
Dec;1784(12):2052-8. doi: 10.1016/j.bbapap.2008.07.013. Epub 2008 Aug 6. PMID:
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275: Yordanov M, Dimitrova P, Patkar S, Saso L, Ivanovska N. Inhibition of
Candida albicans extracellular enzyme activity by selected natural substances
and their application in Candida infection. Can J Microbiol. 2008
Jun;54(6):435-40. doi: 10.1139/w08-029. PMID: 18535628.

276: Firuzi O, Spadaro A, Spadaro C, Riccieri V, Petrucci R, Marrosu G, Saso L.
Protein oxidation markers in the serum and synovial fluid of psoriatic arthritis
patients. J Clin Lab Anal. 2008;22(3):210-5. doi: 10.1002/jcla.20243. PMID:
18484659; PMCID: PMC6649062.

277: Arora S, Vohra P, Kumar A, Tyagi YK, Raj HG, Dawarkanath BS, Saluja D, Saso
L, Parmar VS. Calreticulin transacetylase catalyzed activation of rat tracheal
smooth muscle cell nitric oxide synthase by acetoxycoumarins. Biol Pharm Bull.
2008 Apr;31(4):709-13. doi: 10.1248/bpb.31.709. PMID: 18379067.

278: Rehakova Z, Koleckar V, Cervenka F, Jahodar L, Saso L, Opletal L, Jun D,
Kuca K. DPPH Radical Scavenging Activity of Several Naturally Occurring
Coumarins and Their Synthesized Analogs Measured by the SIA Method. Toxicol Mech
Methods. 2008;18(5):413-8. doi: 10.1080/15376510701511448. PMID: 20020865.

279: Pedersen JZ, Oliveira C, Incerpi S, Kumar V, Fiore AM, De Vito P, Prasad
AK, Malhotra SV, Parmar VS, Saso L. Antioxidant activity of 4-methylcoumarins. J
Pharm Pharmacol. 2007 Dec;59(12):1721-8. doi: 10.1211/jpp.59.12.0015. PMID:
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280: Jones DS, Saso L. Chemistry and biology of antioxidants. J Pharm Pharmacol.
2007 Dec;59(12):1671. doi: 10.1211/jpp.59.12.0009. PMID: 18053329.

281: Riccieri V, Spadaro A, Fuksa L, Firuzi O, Saso L, Valesini G. Specific
oxidative stress parameters differently correlate with nailfold capillaroscopy
changes and organ involvement in systemic sclerosis. Clin Rheumatol. 2008
Feb;27(2):225-30. doi: 10.1007/s10067-007-0769-9. Epub 2007 Oct 27. PMID:
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282: Ognibene E, Bovicelli P, Adriani W, Saso L, Laviola G. Behavioral effects
of 6-bromoflavanone and 5-methoxy-6,8-dibromoflavanone as anxiolytic compounds.
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jan 1;32(1):128-34. doi:
10.1016/j.pnpbp.2007.07.023. Epub 2007 Aug 6. PMID: 17888554.

283: Croce A, Firuzi O, Altieri F, Eufemi M, Agostino R, Priori R, Bombardieri
M, Alessandri C, Valesini G, Saso L. Effect of infliximab on the glycosylation
of IgG of patients with rheumatoid arthritis. J Clin Lab Anal.
2007;21(5):303-14. doi: 10.1002/jcla.20191. PMID: 17847113; PMCID: PMC6649080.

284: Villo L, Danilas K, Metsala A, Kreen M, Vallikivi I, Vija S, Pehk T, Saso
L, Parve O. Synthesis of deoxy sugar esters: a chemoenzymatic stereoselective
approach affording deoxy sugar derivatives also in the form of aldehyde. J Org
Chem. 2007 Jul 20;72(15):5813-6. doi: 10.1021/jo062640b. Epub 2007 Jun 29. PMID:
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285: Shalova IN, Naletova IN, Saso L, Muronetz VI, Izumrudov VA. Interaction of
polyelectrolytes with proteins, 3. Influence of complexing polycations on the
thermoaggregation of oligomeric enzymes. Macromol Biosci. 2007 Jul
9;7(7):929-39. doi: 10.1002/mabi.200700052. PMID: 17582803.

286: Schmalhausen EV, Zhlobek EB, Shalova IN, Firuzi O, Saso L, Muronetz VI.
Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate
dehydrogenase. Food Chem Toxicol. 2007 Oct;45(10):1988-93. doi:
10.1016/j.fct.2007.04.015. Epub 2007 May 3. PMID: 17559999.

287: Artico M, Bronzetti E, Saso L, Felici LM, D'Ambrosio A, Forte F, Grande C,
Ortolani F. Immunohistochemical profile of some neurotransmitters and
neurotrophins in the seminiferous tubules of rats treated by lonidamine. Eur J
Histochem. 2007 Jan-Mar;51(1):19-24. PMID: 17548265.

288: Shalova IN, Cechalova K, Rehakova Z, Dimitrova P, Ognibene E, Caprioli A,
Schmalhausen EV, Muronetz VI, Saso L. Decrease of dehydrogenase activity of
cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of
Alzheimer's disease. Biochim Biophys Acta. 2007 May;1770(5):826-32. doi:
10.1016/j.bbagen.2007.01.014. Epub 2007 Feb 4. PMID: 17324518.

289: Ruiz C, Falcocchio S, Pastor FI, Saso L, Diaz P. Helicobacter pylori EstV:
identification, cloning, and characterization of the first lipase isolated from
an epsilon-proteobacterium. Appl Environ Microbiol. 2007 Apr;73(8):2423-31. doi:
10.1128/AEM.02215-06. Epub 2007 Feb 9. PMID: 17293528; PMCID: PMC1855603.

290: Khanova HA, Markossian KA, Kleimenov SY, Levitsky DI, Chebotareva NA, Golub
NV, Asryants RA, Muronetz VI, Saso L, Yudin IK, Muranov KO, Ostrovsky MA,
Kurganov BI. Effect of alpha-crystallin on thermal denaturation and aggregation
of rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Biophys Chem. 2007
Feb;125(2-3):521-31. doi: 10.1016/j.bpc.2006.11.002. Epub 2006 Nov 21. PMID:
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291: Markossian KA, Khanova HA, Kleimenov SY, Levitsky DI, Chebotareva NA,
Asryants RA, Muronetz VI, Saso L, Yudin IK, Kurganov BI. Mechanism of thermal
aggregation of rabbit muscle glyceraldehyde-3-phosphate dehydrogenase.
Biochemistry. 2006 Nov 7;45(44):13375-84. doi: 10.1021/bi0610707. PMID:
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292: Firuzi O, Mladenka P, Riccieri V, Spadaro A, Petrucci R, Marrosu G, Saso L.
Parameters of oxidative stress status in healthy subjects: their correlations
and stability after sample collection. J Clin Lab Anal. 2006;20(4):139-48. doi:
10.1002/jcla.20122. PMID: 16874810; PMCID: PMC6807518.

293: Firuzi O, Fuksa L, Spadaro C, Bousová I, Riccieri V, Spadaro A, Petrucci R,
Marrosu G, Saso L. Oxidative stress parameters in different systemic rheumatic
diseases. J Pharm Pharmacol. 2006 Jul;58(7):951-7. doi: 10.1211/jpp.58.7.0010.
PMID: 16805955.

294: Falcocchio S, Ruiz C, Pastor FI, Saso L, Diaz P. Identification of a
carboxylesterase-producing Rhodococcus soil isolate. Can J Microbiol. 2005
Sep;51(9):753-8. doi: 10.1139/w05-059. PMID: 16391653.

295: Shalova IN, Asryants RA, Sholukh MV, Saso L, Kurganov BI, Muronetz VI,
Izumrudov VA. Interaction of polyanions with basic proteins, 2(a) : influence of
complexing polyanions on the thermo-aggregation of oligomeric enzymes. Macromol
Biosci. 2005 Dec 15;5(12):1184-92. doi: 10.1002/mabi.200500142. PMID: 16307432.

296: Maranghi F, Mantovani A, Macrì C, Romeo A, Eleuteri P, Leter G, Rescia M,
Spanò M, Saso L. Long-term effects of lonidamine on mouse testes. Contraception.
2005 Oct;72(4):268-72. doi: 10.1016/j.contraception.2005.05.019. PMID: 16181970.

297: Traina ME, Guarino M, Urbani E, Saso L, Eleuteri P, Cordelli E, Rescia M,
Leter G, Spanò M. Lonidamine transiently affects spermatogenesis in pubertal CD1
mice. Contraception. 2005 Oct;72(4):262-7. doi:
10.1016/j.contraception.2005.04.008. PMID: 16181969.

298: Yordanov M, Dimitrova P, Patkar S, Falcocchio S, Xoxi E, Saso L, Ivanovska
N. Ibogaine reduces organ colonization in murine systemic and gastrointestinal
Candida albicans infections. J Med Microbiol. 2005 Jul;54(Pt 7):647-653. doi:
10.1099/jmm.0.45919-0. PMID: 15947429.

299: Daniele C, Dahamna S, Firuzi O, Sekfali N, Saso L, Mazzanti G. Atractylis
gummifera L. poisoning: an ethnopharmacological review. J Ethnopharmacol. 2005
Feb 28;97(2):175-81. doi: 10.1016/j.jep.2004.11.025. Epub 2005 Jan 13. PMID:
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300: Firuzi O, Lacanna A, Petrucci R, Marrosu G, Saso L. Evaluation of the
antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay
and cyclic voltammetry. Biochim Biophys Acta. 2005 Jan 18;1721(1-3):174-84. doi:
10.1016/j.bbagen.2004.11.001. Epub 2004 Dec 22. PMID: 15652192.

301: Firuzi O, Mladenka P, Petrucci R, Marrosu G, Saso L. Hypochlorite
scavenging activity of flavonoids. J Pharm Pharmacol. 2004 Jun;56(6):801-7. doi:
10.1211/0022357023556. PMID: 15231046.

302: Ruiz C, Falcocchio S, Xoxi E, Pastor FI, Diaz P, Saso L. Activation and
inhibition of Candida rugosa and Bacillus-related lipases by saturated fatty
acids, evaluated by a new colorimetric microassay. Biochim Biophys Acta. 2004
Jun 11;1672(3):184-91. doi: 10.1016/j.bbagen.2004.03.010. PMID: 15182938.

303: Firuzi O, Giansanti L, Vento R, Seibert C, Petrucci R, Marrosu G, Agostino
R, Saso L. Hypochlorite scavenging activity of hydroxycinnamic acids evaluated
by a rapid microplate method based on the measurement of chloramines. J Pharm
Pharmacol. 2003 Jul;55(7):1021-7. doi: 10.1211/0022357021314. PMID: 12906760.

304: Grippa E, Gatto MT, Caiola M, Persio D, Tita B, Saso L. Effect of
lonidamine on alpha2-macroglobulin, hemopexin and alpha1-antitrypsin in the rat
testis and epididymis. Res Commun Mol Pathol Pharmacol. 2001;110(3-4):169-82.
PMID: 12760487.

305: Bonanni G, Saso L. Valutazione dell'adesione alle linee guida per il
trattamento farmacologico del paziente asmatico attraverso la somministrazione
di un questionario in farmacia [Evaluation of the adherence to the asthma
guidelines by the administration of a questionnaire in community pharmacies].
Minerva Med. 2003 Feb;94(1):29-40. Italian. PMID: 12719700.

306: Saso L. Effetti delle sostanze d'abuso sulla risposta sessuale [Effects of
drug abuse on sexual response]. Ann Ist Super Sanita. 2002;38(3):289-96.
Italian. PMID: 12645180.

307: Gatto MT, Firuzi O, Agostino R, Grippa E, Borsò A, Spinelli F, Pavan L,
Petrolati M, Petrucci R, Marrosu G, Saso L. Development of a new assay for the
screening of hypochlorous acid scavengers based on reversed-phase high-
performance liquid chromatography. Biomed Chromatogr. 2002 Sep;16(6):404-11.
doi: 10.1002/bmc.174. PMID: 12228898.

308: Leone MG, Abdel HH, Gennaro G, Amici S, Conte D, Romanelli F, Latini M,
Isidori A, Saso L, Silvestrini B. Changes of lipocalin type prostaglandin
D-synthase in the seminal plasma of subfertile man. Res Commun Mol Pathol
Pharmacol. 2001 Jul-Aug;110(1-2):17-25. PMID: 12090353.

309: Bolle P, Evandri MG, Saso L. The controversial efficacy of vitamin E for
human male infertility. Contraception. 2002 Apr;65(4):313-5. doi:
10.1016/s0010-7824(02)00277-9. PMID: 12020785.

310: Leone MG, Haq HA, Saso L. Lipocalin type prostaglandin D-synthase: which
role in male fertility? Contraception. 2002 Apr;65(4):293-5. doi:
10.1016/s0010-7824(02)00280-9. PMID: 12020781.

311: Gatto MT, Tita B, Artico M, Saso L. Recent studies on lonidamine, the lead
compound of the antispermatogenic indazol-carboxylic acids. Contraception. 2002
Apr;65(4):277-8. doi: 10.1016/s0010-7824(02)00289-5. PMID: 12020777.

312: Cheng CY, Mo My, Grima J, Saso L, Tita B, Mruk D, Silvestrini B. Indazole
carboxylic acids in male contraception. Contraception. 2002 Apr;65(4):265-8.
doi: 10.1016/s0010-7824(01)00318-3. PMID: 12020774.

313: Gatto MT, Falcocchio S, Grippa E, Mazzanti G, Battinelli L, Nicolosi G,
Lambusta D, Saso L. Antimicrobial and anti-lipase activity of quercetin and its
C2-C16 3-O-acyl-esters. Bioorg Med Chem. 2002 Feb;10(2):269-72. doi:
10.1016/s0968-0896(01)00275-9. PMID: 11741775.

314: Tita B, Leone MG, Casini ML, Corubolo C, Bordi F, Guidolin D, Fumagalli E,
Romanelli L, Mattioli F, Fehér J, Saso L. Corneal toxicity of xylazine and
clonidine, in combination with ketamine, in the rat. Ophthalmic Res. 2001 Nov-
Dec;33(6):345-52. doi: 10.1159/000055692. PMID: 11721188.

315: Vitalone A, Bordi F, Baldazzi C, Mazzanti G, Saso L, Tita B. Anti-
proliferative effect on a prostatic epithelial cell line (PZ-HPV-7) by Epilobium
angustifolium L. Farmaco. 2001 May-Jul;56(5-7):483-9. doi:
10.1016/s0014-827x(01)01067-9. PMID: 11482783.

316: Tita B, Abdel-Haq H, Vitalone A, Mazzanti G, Saso L. Analgesic properties
of Epilobium angustifolium, evaluated by the hot plate test and the writhing
test. Farmaco. 2001 May-Jul;56(5-7):341-3. doi: 10.1016/s0014-827x(01)01046-1.
PMID: 11482754.

317: Cheng CY, Silvestrini B, Grima J, Mo MY, Zhu LJ, Johansson E, Saso L, Leone
MG, Palmery M, Mruk D. Two new male contraceptives exert their effects by
depleting germ cells prematurely from the testis. Biol Reprod. 2001
Aug;65(2):449-61. doi: 10.1095/biolreprod65.2.449. PMID: 11466213.

318: Befani O, Grippa E, Saso L, Turini P, Mondovì B. Inhibition of monoamine
oxidase by metronidazole. Inflamm Res. 2001 Apr;50 Suppl 2:S136-7. doi:
10.1007/PL00022395. PMID: 11411591.

319: Saso L, Valentini G, Casini ML, Grippa E, Gatto MT, Leone MG, Silvestrini
B. Inhibition of heat-induced denaturation of albumin by nonsteroidal
antiinflammatory drugs (NSAIDs): pharmacological implications. Arch Pharm Res.
2001 Apr;24(2):150-8. doi: 10.1007/BF02976483. PMID: 11339635.

320: Saso L, Grippa E, Gatto MT, Silvestrini B. Inhibition of calcium oxalate
precipitation by bile salts. Int J Urol. 2001 Mar;8(3):124-7. doi:
10.1046/j.1442-2042.2001.00264.x. PMID: 11260337.

321: Riccieri V, Spadaro A, Saso L, Valentini G, Taccari E, Silvestrini B.
Immunohistologic markers of immune activation and changes of glycosylation of
serum proteins in primary Sjögren's syndrome. Clin Exp Rheumatol. 2001 Jan-
Feb;19(1):53-8. PMID: 11247326.

322: Saso L, Silvestrini B. Problemi etici della sperimentazione sull'uomo con
particolare riguardo al consenso informato [Ethical issues of human
experimentation with special reference to informed consent]. Minerva Med. 2000
Oct;91(10):255-65. Italian. PMID: 11236391.

323: Grippa E, Gatto MT, Leone MG, Tita B, Adbel-Haq H, Vitalone A, Silvestrini
B, Saso L. Analysis of lonidamine in rat serum and testis by high performance
liquid chromatography. Biomed Chromatogr. 2001 Feb;15(1):1-8. doi:
10.1002/bmc.14. PMID: 11180293.

324: Saso L, Silvestrini B. Antidenaturant drugs for cataract and other
condensation diseases. Med Hypotheses. 2001 Jan;56(1):114-20. doi:
10.1054/mehy.2000.1128. PMID: 11133267.

325: Abdel-Haq H, Cometa MF, Palmery M, Leone MG, Silvestrini B, Saso L.
Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea
pig isolated trachea. Pharmacol Toxicol. 2000 Nov;87(5):218-22. doi:
10.1034/j.1600-0773.2000.d01-77.x. PMID: 11129501.

326: Grippa E, Pavone F, Gatto MT, Petrucci R, Marrosu G, Silvestrini B, Saso L.
In vitro evaluation of antioxidant activity by electrophoresis and high
performance liquid chromatography. Biochim Biophys Acta. 2000 Dec
15;1524(2-3):171-7. doi: 10.1016/s0304-4165(00)00154-9. PMID: 11113564.

327: Saso L, Tommasino P, Italiano G, Grippa E, Leone MG, Gatto MT, Silvestrini
B. Changes of acute-phase proteins in streptozotocin-induced diabetic rats.
Physiol Res. 2000;49(4):403-9. PMID: 11072799.

328: Saso L, Silvestrini B. La calcolosi renale [Nephrolithiasis]. Recenti Prog
Med. 2000 Jul-Aug;91(7-8):388-95. Italian. PMID: 10932926.

329: Mazzanti G, Mascellino MT, Battinelli L, Coluccia D, Manganaro M, Saso L.
Antimicrobial investigation of semipurified fractions of Ginkgo biloba leaves. J
Ethnopharmacol. 2000 Jul;71(1-2):83-8. doi: 10.1016/s0378-8741(99)00179-8. PMID:
10904149.

330: Leone MG, Grippa E, Guidolin D, Tita B, Abdel-Haq H, Gatto MT, Bordi F,
Cheng CY, Silvestrini B, Saso L. Effects of lonidamine on testicular and
epididymal proteins in the rat. Reprod Toxicol. 2000 May-Jun;14(3):257-63. doi:
10.1016/s0890-6238(00)00076-9. PMID: 10838127.

331: Abdel-Haq H, Giacomelli S, Palmery M, Leone MG, Saso L, Silvestrini B.
Aflatoxins inhibit prolactin secretion by rat pituitary cells in culture. Drug
Chem Toxicol. 2000 May;23(2):381-6. doi: 10.1081/dct-100100123. PMID: 10826104.

332: Abdel-Haq H, Palmery M, Leone MG, Saso L, Silvestrini B. Stimulation of
guinea pig isolated atria by aflatoxins. Toxicol In Vitro. 2000 Jun;14(3):193-7.
doi: 10.1016/s0887-2333(00)00013-8. PMID: 10806369.

333: Abdel-Haq H, Palmery M, Leone MG, Saso L, Silvestrini B. Relaxant effects
of aflatoxins on isolated guinea pig trachea. Toxicol Sci. 2000
May;55(1):162-70. doi: 10.1093/toxsci/55.1.162. PMID: 10788571.

334: Grippa E, Santini L, Castellano G, Gatto MT, Leone MG, Saso L. Simultaneous
determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and
oxyphenbutazone in equine serum by high-performance liquid chromatography. J
Chromatogr B Biomed Sci Appl. 2000 Jan 28;738(1):17-25. doi:
10.1016/s0378-4347(99)00478-8. PMID: 10778922.

335: Saso L, Bonanni G, Grippa E, Gatto MT, Leone MG, Silvestrini B. Interaction
of hyaluronic acid with mucin, evaluated by gel permeation chromatography. Res
Commun Mol Pathol Pharmacol. 1999;104(3):277-84. PMID: 10741378.

336: Saso L, Grippa E, Gatto MT, Leone MG, Silvestrini B. Inhibition of heat-
induced aggregation of beta- and gamma-crystallin by alpha-crystallin evaluated
by gel permeation HPLC. Biochemistry (Mosc). 2000 Feb;65(2):208-12. PMID:
10713549.

337: Saso L, Valentini G, Riccieri V, Spadaro A, Zoppini A, Silvestrini B.
Changes of glycosylation of serum proteins in Sjögren's syndrome: correlation
with interleukin-6 and soluble interleukin-2 receptor. IUBMB Life. 1999
Oct;48(4):385-90. doi: 10.1080/713803529. PMID: 10632566.

338: Grippa E, Valla R, Battinelli L, Mazzanti G, Saso L, Silvestrini B.
Inhibition of Candida rugosa lipase by berberine and structurally related
alkaloids, evaluated by high-performance liquid chromatography. Biosci
Biotechnol Biochem. 1999 Sep;63(9):1557-62. doi: 10.1271/bbb.63.1557. PMID:
10540743.

339: Saso L, Valentini G, Mattei E, Panzironi C, Casini ML, Grippa E,
Silvestrini B. Stabilization of rat serum proteins following oral administration
of fish oil. Arch Pharm Res. 1999 Oct;22(5):485-90. doi: 10.1007/BF02979157.
PMID: 10549576.

340: Leone MG, Saso L, Cheng CY, Silvestrini B. Micropurification of beta- and
gamma-crystallins from rabbit aqueous humor. Int J Biol Macromol. 1999
Nov;26(2-3):167-71. doi: 10.1016/s0141-8130(99)00078-1. PMID: 10517525.

341: Cazzolla N, Saso L, Grima J, Leone MG, Grippa E, Cheng CY, Silvestrini B.
Development of an enzyme-linked immunosorbent assay, using a monoclonal antibody
against alpha2-macroglobulin, for the diagnosis of systemic lupus erythematosus.
Clin Biochem. 1999 Jun;32(4):249-55. doi: 10.1016/s0009-9120(99)00010-7. PMID:
10463816.

342: Saso L, Tommasino P, Grippa E, Leone MG, Silvestrini B. Micromethods for
the analysis of tear proteins in pharmacological studies. Res Commun Mol Pathol
Pharmacol. 1999 Feb;103(2):149-65. PMID: 10461682.

343: Saso L, Leone MG, Mo MY, Grippa E, Cheng CY, Silvestrini B. Differential
changes in alpha2-macroglobulin and hemopexin in brain and liver in response to
acute inflammation. Biochemistry (Mosc). 1999 Jul;64(7):839-44. PMID: 10424910.

344: Saso L, Valentini G, Leone MG, Grippa E, Guglielmi R, Paris L, Cantore G,
Silvestrini B. Changes in concanavalin A-reactive proteins in neurological
disorders. J Clin Lab Anal. 1999;13(4):158-65. doi:
10.1002/(sici)1098-2825(1999)13:4<158::aid-jcla4>3.0.co;2-0. PMID: 10414595;
PMCID: PMC6807750.

345: Saso L, Valentini G, Leone MG, Grippa E, Silvestrini B. Development of an
in vitro assay for the screening of substances capable of dissolving calcium
oxalate crystals. Urol Int. 1998;61(4):210-4. doi: 10.1159/000030331. PMID:
10364751.

346: Saso L, Valentini G, Casini ML, Mattei E, Braghiroli L, Mazzanti G,
Panzironi C, Grippa E, Silvestrini B. Inhibition of protein denaturation by
fatty acids, bile salts and other natural substances: a new hypothesis for the
mechanism of action of fish oil in rheumatic diseases. Jpn J Pharmacol. 1999
Jan;79(1):89-99. doi: 10.1254/jjp.79.89. PMID: 10082322.

347: Saso L, Valentini G, Grippa E, Leone MG, Silvestrini B. Effect of selected
substances on heat-induced aggregation of albumin, IgG and lysozyme. Res Commun
Mol Pathol Pharmacol. 1998 Oct;102(1):15-28. PMID: 9920343.

348: Saso L, Valentini G, Giardino AM, Spadaro A, Riccieri V, Zoppini A,
Silvestrini B. Changes of glycosylation of serum proteins in psoriatic
arthritis, studied by enzyme-linked lectin assay (ELLA), using concanavalin A.
Biochem Mol Biol Int. 1998 Dec;46(5):867-75. doi: 10.1080/15216549800204412.
PMID: 9861440.

349: Saso L, Leone MG, Sorrentino C, Giacomelli S, Silvestrini B, Grima J, Li
JC, Samy E, Mruk D, Cheng CY. Quantification of prostaglandin D synthetase in
cerebrospinal fluid: a potential marker for brain tumor. Biochem Mol Biol Int.
1998 Nov;46(4):643-56. doi: 10.1080/15216549800204172. PMID: 9844724.

350: Saso L, Casini ML, Valentini G, Mattei E, Panzironi C, Silvestrini B.
Development of an HPLC assay to study the effect of endogenous and exogenous
substances on heat-induced aggregation of human serum albumin. Clin Chem Lab
Med. 1998 Mar;36(3):155-62. doi: 10.1515/CCLM.1998.029. PMID: 9589803.

351: Saso L, Valentini G, Casini ML, Mattei E, Panzironi C, Silvestrini B.
Development of a turbidimetric assay to study the effect of urinary components
on calcium oxalate precipitation. Urol Int. 1998;60(1):47-52. doi:
10.1159/000030202. PMID: 9519421.

352: Li AH, Zwain IH, Pineau C, Cazzolla N, Saso L, Silvestrini B, Bardin CW,
Cheng CY. Response of alpha 2-macroglobulin messenger ribonucleic acid
expression to acute inflammation in the testis is different from the response in
the liver and brain. Biol Reprod. 1994 Jun;50(6):1287-96. doi:
10.1095/biolreprod50.6.1287. PMID: 7521677.

353: Leone MG, Saso L, Del Vecchio A, Mo MY, Silvestrini B, Cheng CY.
Micropurification of two human cerebrospinal fluid proteins by high performance
electrophoresis chromatography. J Neurochem. 1993 Aug;61(2):533-40. doi:
10.1111/j.1471-4159.1993.tb02156.x. PMID: 8336140.

354: Saso L, Silvestrini B, Cheng CY. The use of high-performance
electrophoresis chromatography for the micropurification of cerebrospinal fluid
proteins in the rat. Anal Biochem. 1993 Aug 1;212(2):315-24. doi:
10.1006/abio.1993.1336. PMID: 8214572.

355: Saso L, Silvestrini B, Guglielmotti A, Lahita R, Cheng CY. Abnormal
glycosylation of alpha 2-macroglobulin, a non-acute-phase protein in patients
with autoimmune diseases. Inflammation. 1993 Aug;17(4):465-79. doi:
10.1007/BF00916586. PMID: 7691738.

356: Saso L, Silvestrini B, Lahita R, Cheng CY. Changes of immunoreactivity in
alpha 1-antitrypsin in patients with autoimmune diseases. Inflammation. 1993
Jun;17(3):383-400. doi: 10.1007/BF00918999. PMID: 7687239.

357: Guglielmotti A, Silvestrini B, Saso L, Zwain I, Cheng CY. Chronic
inflammatory response in the rat can be blocked by bindarit. Biochem Mol Biol
Int. 1993 Mar;29(4):747-56. PMID: 7683947.

358: Zwain IH, Grima J, Stahler MS, Saso L, Cailleau J, Verhoeven G, Bardin CW,
Cheng CY. Regulation of Sertoli cell alpha 2-macroglobulin and clusterin (SGP-2)
secretion by peritubular myoid cells. Biol Reprod. 1993 Jan;48(1):180-7. doi:
10.1095/biolreprod48.1.180. PMID: 7678201.

359: Saso L, Silvestrini B, Zwain I, Guglielmotti A, Luparini MR, Cioli V, Cheng
CY. Abnormal glycosylation of hemopexin in arthritic rats can be blocked by
bindarit. J Rheumatol. 1992 Dec;19(12):1859-67. PMID: 1284132.

360: Schlegel PN, Matthews GJ, Cichon Z, Aulitzky WK, Cheng CY, Chen CL, Saso L,
Goldstein M, Jänne OA, Bardin CW, et al. Clusterin production in the obstructed
rabbit kidney: correlations with loss of renal function. J Am Soc Nephrol. 1992
Nov;3(5):1163-71. doi: 10.1681/ASN.V351163. PMID: 1482755.

361: Silvestrini B, Guglielmotti A, Saso L, Milanese C, Melanitou E, Grima J,
Cheng CY. Development of an enzyme-linked immunosorbent assay with a monoclonal
antibody prepared against alpha 1-antitrypsin for diagnostic screening of
inflammatory disorders. Clin Chem. 1990 Feb;36(2):277-82. PMID: 1689223.

362: Silvestrini B, Guglielmotti A, Saso L, Cheng CY. Changes in concanavalin
A-reactive proteins in inflammatory disorders. Clin Chem. 1989
Nov;35(11):2207-11. PMID: 2479495.